Pub. Date : 2011 Oct
PMID : 21690245
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Miscoding mutations of the TET2 gene, which encodes the alpha-ketoglutarate-dependent enzyme that catalyses the conversion of 5-methylcytosine to 5-hydroxymethylcytosine, thus producing DNA demethylation, have been detected in 10-25% of acute myeloid leukaemias lacking IDH1/2 mutations. | 5-hydroxymethylcytosine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |