nucleophosmin 1 ; Mus musculus






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1 1495750 Studies of actinomycin D induced B23-translocation in P388D1 cells implanted in DBA/2 mice. Oncology 1992 4
2 2439199 Nucleolar protein B23 translocation after doxorubicin treatment in murine tumor cells. Cancer Res 1987 Jul 15 1
3 2720680 Cross-linkage of nucleophosmin in tumor cells by nitrogen mustard. Cancer Res 1989 Jun 15 3
4 2910487 Cyclosporin A and verapamil enhancement of daunorubicin-produced nucleolar protein B23 translocation in daunorubicin-resistant and -sensitive human and murine tumor cells. Cancer Res 1989 Feb 1 3
5 3141428 The nuclear matrix protein, numatrin (B23), is associated with growth factor-induced mitogenesis in Swiss 3T3 fibroblasts and with T lymphocyte proliferation stimulated by lectins and anti-T cell antigen receptor antibody. J Cell Biol 1988 Nov 6
6 3301855 "Numatrin," a nuclear matrix protein associated with induction of proliferation in B lymphocytes. J Biol Chem 1987 Aug 15 4
7 7990980 Structure-activity relationship of covalently dimerized insulin derivatives: correlation of partial agonist efficacy with cross-linkage at lysine B29. Naunyn Schmiedebergs Arch Pharmacol 1994 Aug 1
8 9819383 Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity. Mol Cell Biol 1998 Dec 6
9 10339585 Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha. Proc Natl Acad Sci U S A 1999 May 25 2
10 11280786 Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis. Cancer Res 2001 Mar 1 2
11 11522649 Role of signal transducer and activator of transcription 5 in nucleophosmin/ anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells. Cancer Res 2001 Sep 1 1
12 11751994 Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma. J Immunol 2002 Jan 1 1
13 12555065 Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice. Oncogene 2003 Jan 30 1
14 12748172 Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA). J Biol Chem 2003 Aug 8 2
15 14586401 Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive Jun kinase. Oncogene 2003 Oct 30 1
16 15588951 NPM/ALK downregulates p27Kip1 in a PI-3K-dependent manner. Exp Hematol 2004 Dec 1
17 15895073 Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target. Nat Med 2005 Jun 1
18 15902287 What have we learnt from mouse models of NPM-ALK-induced lymphomagenesis? Leukemia 2005 Jul 2
19 16170336 Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3. Lab Invest 2005 Dec 7
20 16277692 Association between anti-nucleophosmin and anti-cardiolipin antibodies in (NZW x BXSB)F1 mice and human systemic lupus erythematosus. Arthritis Res Ther 2005 2
21 16469875 SHP1 tyrosine phosphatase negatively regulates NPM-ALK tyrosine kinase signaling. Blood 2006 May 15 1
22 16870143 Inducible and reversible suppression of Npm1 gene expression using stably integrated small interfering RNA vector in mouse embryonic stem cells. Biochem Biophys Res Commun 2006 Sep 8 2
23 16888916 [Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice]. Verh Dtsch Ges Pathol 2003 1
24 16909118 Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf. Oncogene 2007 Feb 8 1
25 17556599 Oxygen tension regulates survival and fate of mouse central nervous system precursors at multiple levels. Stem Cells 2007 Sep 1
26 18685609 Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis. Leukemia 2008 Nov 5
27 19088198 Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1). Proc Natl Acad Sci U S A 2008 Dec 30 1
28 19249873 ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors. Biochemistry 2009 Apr 28 6
29 20303727 Involvement of nucleophosmin/B23 in the cellular response to curcumin. J Nutr Biochem 2011 Jan 14
30 20505363 Translationally controlled tumor protein interacts with nucleophosmin during mitosis in ES cells. Cell Cycle 2010 Jun 1 1
31 20683949 Thiazolidinediones inhibit hepatocarcinogenesis in hepatitis B virus-transgenic mice by peroxisome proliferator-activated receptor gamma-independent regulation of nucleophosmin. Hepatology 2010 Aug 1
32 21724521 Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro. Environ Health Perspect 2011 Jul 5
33 21835027 Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast. BMC Cell Biol 2011 Aug 11 2
34 23027902 S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1-GAPDH death cascade. J Cell Biol 2012 Oct 1 2
35 23226219 A knock-in Npm1 mutation in mice results in myeloproliferation and implies a perturbation in hematopoietic microenvironment. PLoS One 2012 1
36 24282525 RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. PLoS One 2013 2
37 25026277 The ALK inhibitor ASP3026 eradicates NPM-ALK⁺ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget 2014 Jul 30 1
38 25279177 Synergistic interactions of the anti-casein kinase 2 CIGB-300 peptide and chemotherapeutic agents in lung and cervical preclinical cancer models. Mol Clin Oncol 2014 Nov 1
39 27050906 mTOR transcriptionally and post-transcriptionally regulates Npm1 gene expression to contribute to enhanced proliferation in cells with Pten inactivation. Cell Cycle 2016 May 18 1
40 27187980 Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain. Environ Health Perspect 2016 Oct 4
41 27253419 14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression. Sci Rep 2016 Jun 2 1
42 27510036 Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status. J Biol Chem 2016 Sep 23 1
43 28055106 Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia. Cancer 2017 May 1 7
44 31340850 Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK<sup>+</sup> T-cell lymphoma. J Hematol Oncol 2019 Jul 24 1
45 31434245 Proteomic Phosphosite Analysis Identified Crucial NPM-ALK-Mediated NIPA Serine and Threonine Residues. Int J Mol Sci 2019 Aug 20 7
46 31654627 Methotrexate significantly induces apoptosis by inhibiting STAT3 activation in NPM-ALK-positive ALCL cells. Biochem Pharmacol 2019 Dec 1
47 32007256 Nucleophosmin contributes to vascular inflammation and endothelial dysfunction in atherosclerosis progression. J Thorac Cardiovasc Surg 2021 May 1
48 34131282 A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA. Leukemia 2021 Oct 1
49 34134693 Doxorubicin induces an alarmin-like TLR4-dependent autocrine/paracrine action of Nucleophosmin in human cardiac mesenchymal progenitor cells. BMC Biol 2021 Jun 16 4
50 35140112 PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy. J Immunother Cancer 2022 Feb 1