inosine triphosphatase ; Homo sapiens






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1 138680 Structure and function of the two heads of the myosin molecule. IV. Physiological functions of various reaction intermediates in myosin adenosinetriphosphatase, studied by the interaction between actomyosin and 8-bromoadenosine triphosphate. J Biochem 1976 Dec 6
2 192642 Hydrolysis of nucleoside triphosphate in plasma membranes of the hepatocytes of normal, regenerating and foetal livers and in cancer cells of hepatomas. Folia Histochem Cytochem (Krakow) 1976 1
3 1648487 Evidence for a direct interaction of Rev protein with nuclear envelop mRNA-translocation system. Eur J Biochem 1991 Jul 1 1
4 1851409 Synovial fluid pyrophosphate and nucleoside triphosphate pyrophosphatase: comparison between normal and diseased and between inflamed and non-inflamed joints. Ann Rheum Dis 1991 Apr 1
5 1963521 Effect of dipyridamole on inosine triphosphate pyrophosphohydrolase activity and inosine triphosphate content in fresh human erythrocytes incubated with adenosine. Acta Biochim Pol 1990 9
6 1965140 The Mr 46,000 nuclear scaffold ATP-binding protein: identification of the putative nucleoside triphosphatase by proteolysis and monoclonal antibodies directed against lamins A/C. Cell Growth Differ 1990 Nov 1
7 2156508 Acid nucleoside triphosphatase: partial purification and characterization of a new enzyme from human serum. Biochem Int 1990 2
8 2514792 Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast derived tissue plasminogen activator. Biochemistry 1989 Sep 19 2
9 2836113 Purine metabolism in normal and ITP-pyrophosphohydrolase-deficient human erythrocytes. Clin Chim Acta 1988 Feb 15 3
10 3017213 Partial purification of a nucleoside triphosphatase from the inner membrane of the chloroplast envelope of pea. Arch Biochem Biophys 1986 Aug 1 5
11 3036904 Direct stimulation of nucleoside triphosphatase activity in human ovarian nuclear membranes by human chorionic gonadotropin. J Clin Endocrinol Metab 1987 Aug 2
12 6291940 An RNA-dependent nucleoside triphosphate hydrolase from Krebs-II ascites tumor cells. Detection and preliminary characterization. Eur J Biochem 1982 Oct 1
13 6300087 Nucleotide triphosphate utilization by cardiac and skeletal muscle sarcoplasmic reticulum. Further evidence for an alternative substrate hydrolysis cycle and the effect of calcium NTPase purification. J Biol Chem 1983 Apr 10 8
14 7487072 Expression, isolation, and characterization of the hepatitis C virus ATPase/RNA helicase. Arch Biochem Biophys 1995 Oct 20 3
15 7609038 Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase II, a DExH box RNA helicase. J Virol 1995 Aug 1
16 8380474 RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria. J Virol 1993 Feb 1
17 8396675 Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes. J Virol 1993 Oct 4
18 8811006 Characterization of the NTPase activity of Japanese encephalitis virus NS3 protein. J Gen Virol 1996 Sep 3
19 9094652 Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells. J Virol 1997 May 2
20 9215801 Oxidation of nuclear membrane cholesterol inhibits nucleoside triphosphatase activity. Free Radic Biol Med 1997 6
21 9573237 The nucleoside triphosphatase and helicase activities of vaccinia virus NPH-II are essential for virus replication. J Virol 1998 Jun 1
22 9657959 Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein. Virology 1998 Jul 5 2
23 9780054 Bluetongue virus core protein VP4 has nucleoside triphosphate phosphohydrolase activity. J Gen Virol 1998 Oct 2
24 9811740 RNA 5'-triphosphatase, nucleoside triphosphatase, and guanylyltransferase activities of baculovirus LEF-4 protein. J Virol 1998 Dec 4
25 10092010 Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein. J Gen Virol 1999 Mar 4
26 10497107 Nucleoside triphosphatase and RNA helicase activities associated with GB virus B nonstructural protein 3. Virology 1999 Sep 1 1
27 10937433 ATPase and GTPase activities copurifying with GTP-binding proteins in E. coli. J Mol Microbiol Biotechnol 2000 Jul 7
28 10961691 ATP-binding domain of NTPase/helicase as a target for hepatitis C antiviral therapy. Acta Biochim Pol 2000 4
29 11238848 Purification and characterization of West Nile virus nucleoside triphosphatase (NTPase)/helicase: evidence for dissociation of the NTPase and helicase activities of the enzyme. J Virol 2001 Apr 5
30 11278832 Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene. J Biol Chem 2001 Jun 1 5
31 11413375 The inhibition of cAMP-dependent protein kinase by full-length hepatitis C virus NS3/4A complex is due to ATP hydrolysis. J Gen Virol 2001 Jul 3
32 11538660 Characterization of nucleoside triphosphatase activity in isolated pea nuclei and its photoreversible regulation by light. Plant Physiol 1986 4
33 11697897 Hepatitis C virus NS3 NTPase/helicase: different stereoselectivity in nucleoside triphosphate utilisation suggests that NTPase and helicase activities are coupled by a nucleotide-dependent rate limiting step. J Mol Biol 2001 Nov 2 14
34 11959550 Characterization of imidazo[4,5-d]pyridazine nucleosides as modulators of unwinding reaction mediated by West Nile virus nucleoside triphosphatase/helicase: evidence for activity on the level of substrate and/or enzyme. Antimicrob Agents Chemother 2002 May 4
35 12206878 Nucleotide triphosphatase/helicase of hepatitis C virus as a target for antiviral therapy. Antiviral Res 2002 Sep 4
36 12237426 Genome sequence analysis of Tamana bat virus and its relationship with the genus Flavivirus. J Gen Virol 2002 Oct 1
37 12384777 Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency. Hum Genet 2002 Oct 4
38 12436200 DNA polymorphisms in ITPA including basis of inosine triphosphatase deficiency. J Hum Genet 2002 4
39 12463757 Key role of template sequence for primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry 2002 Dec 10 1
40 13976534 The fine localization of nucleoside triphosphatase activity in the retina of the frog. J Cell Biol 1963 May 3
41 14561097 Potent inhibition of NTPase/helicase of the West Nile Virus by ring-expanded ("fat") nucleoside analogues. J Med Chem 2003 Oct 23 3
42 15167706 Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). Pharmacogenetics 2004 Mar 9
43 15220459 Human coronavirus 229E nonstructural protein 13: characterization of duplex-unwinding, nucleoside triphosphatase, and RNA 5'-triphosphatase activities. J Virol 2004 Jul 8
44 15243983 A Japanese case with inosine triphosphate pyrophosphohydrolase deficiency attributable to an enzymatic defect in white blood cells. J Inherit Metab Dis 2004 2
45 15322947 Distribution of ITPA P32T alleles in multiple world populations. J Hum Genet 2004 1
46 15564886 Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine. Pharmacogenetics 2004 Nov 1
47 15571265 Mutation in the ITPA gene predicts intolerance to azathioprine. Nucleosides Nucleotides Nucleic Acids 2004 Oct 6
48 15571266 Allele frequency of inosine triphosphate pyrophosphatase gene polymorphisms in a Japanese population. Nucleosides Nucleotides Nucleic Acids 2004 Oct 4
49 15946879 Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population. Mol Genet Metab 2005 Aug 10
50 16214825 Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study. Clin Chem 2005 Dec 7