Protein Name inosine triphosphatase
Organism Homo sapiens
Gene ID 3704
Gene Symbol


UniProt Q9BY32 (ITPA_HUMAN), A0A0S2Z3W7 (A0A0S2Z3W7_HUMAN), Q8WWI0 (Q8WWI0_HUMAN), A0A0S2Z423 (A0A0S2Z423_HUMAN)
Relationships Total Number of functionally related compound(s) : 170
Total Number of Articles : 226

inosine triphosphatase

Gene Summary

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

  • inosine triphosphate pyrophosphatase
  • epididymis secretory sperm binding protein
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Click to show/hide the synonyms