Pub. Date : 2002 May
PMID : 11959550
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Characterization of imidazo[4,5-d]pyridazine nucleosides as modulators of unwinding reaction mediated by West Nile virus nucleoside triphosphatase/helicase: evidence for activity on the level of substrate and/or enzyme. | imidazo[4,5-d]pyridazine nucleosides | inosine triphosphatase | Homo sapiens |
| 2 | In the present study we describe the synthesis and properties of some nucleoside analogues that interact with double-stranded DNA but that, in contrast, facilitate the unwinding reaction mediated by West Nile (WN) virus nucleoside triphosphatase (NTPase)/helicase. | Nucleosides | inosine triphosphatase | Homo sapiens |
| 3 | In the present study we describe the synthesis and properties of some nucleoside analogues that interact with double-stranded DNA but that, in contrast, facilitate the unwinding reaction mediated by West Nile (WN) virus nucleoside triphosphatase (NTPase)/helicase. | Nucleosides | inosine triphosphatase | Homo sapiens |
| 4 | Comparative studies performed with the related NTPase/helicase from hepatitis C virus revealed that the extent of the effects mediated by imidazo[4,5-d]pyridazine nucleosides is enzyme specific. | imidazo[4,5-d]pyridazine nucleosides | inosine triphosphatase | Homo sapiens |