Pub. Date : 2003 Oct 23
PMID : 14561097
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Potent inhibition of NTPase/helicase of the West Nile Virus by ring-expanded ("fat") nucleoside analogues. | Nucleosides | inosine triphosphatase | Homo sapiens |
| 2 | However, at concentrations >500 muM of RENs and the ATP concentrations >10 times the K(m) value of the enzyme, a significant activation of NTPase activity was observed. | Adenosine Triphosphate | inosine triphosphatase | Homo sapiens |
| 3 | This activating effect underwent further dramatic enhancement (>1000%) by further increases in ATP concentration in the reaction mixture, suggesting that the viral helicase and NTPase reactions are not coupled. | Adenosine Triphosphate | inosine triphosphatase | Homo sapiens |