Title : Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

Pub. Date : 2004 Mar

PMID : 15167706






9 Functional Relationships(s)
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Protein Name
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1 Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). Azathioprine inosine triphosphatase Homo sapiens
2 Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). Azathioprine inosine triphosphatase Homo sapiens
3 Inosine triphosphate pyrophosphatase (ITPase) deficiency results in the benign accumulation of the inosine nucleotide ITP. Inosine Nucleotides inosine triphosphatase Homo sapiens
4 Inosine triphosphate pyrophosphatase (ITPase) deficiency results in the benign accumulation of the inosine nucleotide ITP. Inosine Nucleotides inosine triphosphatase Homo sapiens
5 Inosine triphosphate pyrophosphatase (ITPase) deficiency results in the benign accumulation of the inosine nucleotide ITP. Inosine Triphosphate inosine triphosphatase Homo sapiens
6 6-MP is activated through a 6-thio-IMP intermediate and, in ITPase deficient patients, potentially toxic 6-thio-ITP is predicted to accumulate. Mercaptopurine inosine triphosphatase Homo sapiens
7 6-MP is activated through a 6-thio-IMP intermediate and, in ITPase deficient patients, potentially toxic 6-thio-ITP is predicted to accumulate. 6-thio-itp inosine triphosphatase Homo sapiens
8 The association between polymorphism in the ITPA gene and adverse drug reactions to AZA therapy was studied in patients treated for inflammatory bowel disease. Azathioprine inosine triphosphatase Homo sapiens
9 Polymorphism in the ITPA gene predicts AZA intolerance. Azathioprine inosine triphosphatase Homo sapiens