adenylate cyclase 5 ; Mus musculus






48 Article(s)
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1 10799557 The type 8 adenylyl cyclase is critical for Ca2+ stimulation of cAMP accumulation in mouse parotid acini. J Biol Chem 2000 May 12 1
2 11602186 Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase. Cell Signal 2001 Oct 3
3 11805091 Zinc inhibition of cAMP signaling. J Biol Chem 2002 Apr 5 3
4 12223546 Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase. J Neurosci 2002 Sep 15 3
5 12869393 Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation. Circ Res 2003 Aug 22 1
6 16325780 Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors. Biochem Biophys Res Commun 2006 Jan 13 1
7 16537460 Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action. Proc Natl Acad Sci U S A 2006 Mar 7 3
8 17068292 The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6. Circ Res 2006 Nov 24 7
9 17229090 Role of the calcium modulated cyclases in the development of the retinal projections. Eur J Neurosci 2006 Dec 1
10 17410641 Markedly attenuated acute and chronic pain responses in mice lacking adenylyl cyclase-5. Genes Brain Behav 2007 Mar 3
11 18468583 Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting. Biol Psychiatry 2008 Aug 15 1
12 18673448 Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. J Neurochem 2008 Oct 5
13 19307450 Characterization of mouse heart adenylyl cyclase. J Pharmacol Exp Ther 2009 Jun 5
14 19405150 Mice lacking adenylyl cyclase-5 cope badly with repeated restraint stress. J Neurosci Res 2009 Oct 1
15 19793969 Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning. J Neurosci 2009 Sep 30 2
16 19922557 Inhibition of specific adenylyl cyclase isoforms by lithium and carbamazepine, but not valproate, may be related to their antidepressant effect. Bipolar Disord 2009 Dec 17
17 20156488 Dopaminergic dysregulation in mice selectively bred for excessive exercise or obesity. Behav Brain Res 2010 Jul 11 1
18 20231277 AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors. J Biol Chem 2010 May 7 2
19 20818929 The β-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage, and increases extracellular signal-regulated kinase signaling in the heart of C57BL/6 mice. Rejuvenation Res 2010 Dec 1
20 21131397 Paradoxical attenuation of β2-AR function in airway smooth muscle by Gi-mediated counterregulation in transgenic mice overexpressing type 5 adenylyl cyclase. Am J Physiol Lung Cell Mol Physiol 2011 Mar 6
21 21193983 Mice lacking adenylyl cyclase type 5 (AC5) show increased ethanol consumption and reduced ethanol sensitivity. Psychopharmacology (Berl) 2011 May 9
22 21282557 Stimulation of renin secretion by catecholamines is dependent on adenylyl cyclases 5 and 6. Hypertension 2011 Mar 1
23 22505646 Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase. Am J Physiol Heart Circ Physiol 2012 Jun 15 4
24 22850613 Pharmacological stimulation of type 5 adenylyl cyclase stabilizes heart rate under both microgravity and hypergravity induced by parabolic flight. J Pharmacol Sci 2012 1
25 22932702 The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatum. Sci Signal 2012 Aug 28 2
26 23020244 Common mechanisms for calorie restriction and adenylyl cyclase type 5 knockout models of longevity. Aging Cell 2012 Dec 1
27 23063718 The dorsal striatum expressing adenylyl cyclase-5 controls behavioral sensitivity of the righting reflex to high-dose ethanol. Brain Res 2012 Dec 13 8
28 23536361 Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway. Circulation 2013 Apr 23 6
29 23624627 Adenylyl cyclase type 5 in cardiac disease, metabolism, and aging. Am J Physiol Heart Circ Physiol 2013 Jul 1 4
30 23957304 'Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption'. Aging Cell 2014 Feb 3
31 24944202 Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle. Am J Physiol Cell Physiol 2014 Aug 15 1
32 25164669 Inhibition of adenylyl cyclase type 5 prevents L-DOPA-induced dyskinesia in an animal model of Parkinson's disease. J Neurosci 2014 Aug 27 2
33 25378213 Adenylyl cyclase-5 in the dorsal striatum function as a molecular switch for the generation of behavioral preferences for cue-directed food choices. Mol Brain 2014 Nov 7 3
34 25732192 Adenylyl Cyclase Type 5 Deficiency Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes 2015 Jul 1
35 26613416 Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling. Elife 2015 Nov 27 2
36 26941173 A Food and Drug Administration-Approved Antiviral Agent that Inhibits Adenylyl Cyclase Type 5 Protects the Ischemic Heart Even When Administered after Reperfusion. J Pharmacol Exp Ther 2016 May 7
37 27117748 Disruption of Epac1 protects the heart from adenylyl cyclase type 5-mediated cardiac dysfunction. Biochem Biophys Res Commun 2016 Jun 17 1
38 27826057 Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease. J Hepatol 2017 Mar 3
39 28887652 Disruption of adenylyl cyclase type 5 mimics exercise training. Basic Res Cardiol 2017 Sep 8 2
40 29042084 Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease. Kidney Int 2018 Feb 6
41 31009605 Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β<sub>1</sub>-adrenoceptor-mediated inotropic response. J Mol Cell Cardiol 2019 Jun 2
42 31752385 Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D<sub>1</sub> and D<sub>2</sub> Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening. Cells 2019 Nov 19 1
43 31812254 Reduced Neuronal cAMP in the Nucleus Accumbens Damages Blood-Brain Barrier Integrity and Promotes Stress Vulnerability. Biol Psychiatry 2020 Mar 15 7
44 32229518 Emotional Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5-CPEB3-GluA1 Pathway. J Neurosci 2020 Apr 22 1
45 33279641 The CUL3/neddylation inhibitor MLN4924 reduces ethanol-induced locomotor sensitization and inflammatory pain allodynia in mice. Behav Brain Res 2021 Feb 5 1
46 34572144 Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose. Cells 2021 Sep 21 2
47 34645939 Targeting adipocytic discoidin domain receptor 2 impedes fat gain while increasing bone mass. Cell Death Differ 2022 Apr 1
48 35148678 Vidarabine, an anti-herpes agent, prevents occlusal-disharmony-induced cardiac dysfunction in mice. J Physiol Sci 2022 Feb 11 1