lysine acetyltransferase 5 ; Homo sapiens






140 Article(s)
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1 8557695 Selective activation of T cell kinase p56lck by Herpesvirus saimiri protein tip. J Biol Chem 1996 Jan 12 1
2 10096020 Tip60 acetylates six lysines of a specific class in core histones in vitro. Genes Cells 1998 Dec 7
3 10720489 Tip60 inhibits activation of CREB protein by protein kinase A. Biochem Biophys Res Commun 2000 Mar 24 1
4 11971970 Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function. Mol Cell Biol 2002 May 1
5 12110674 A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3. J Biol Chem 2002 Sep 20 3
6 12353039 Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. Nature 2002 Sep 26 2
7 12468530 Tip60 acetyltransferase activity is controlled by phosphorylation. J Biol Chem 2003 Feb 14 2
8 15310756 Role of the histone acetyl transferase Tip60 in the p53 pathway. J Biol Chem 2004 Oct 22 1
9 15969986 Induction of thyroid papillary carcinoma cell proliferation by estrogen is associated with an altered expression of Bcl-xL. Cancer J 2005 Mar-Apr 3
10 15985650 cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells. Am J Physiol Renal Physiol 2006 Jan 4
11 16103124 A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein. J Biol Chem 2005 Nov 4 1
12 16501607 p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation. Oncogene 2006 Jul 13 3
13 16603769 The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM. J Biol Chem 2006 Jun 9 2
14 16844118 Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. FEBS Lett 2006 Aug 7 2
15 17189186 Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 2006 Dec 28 3
16 17223684 Catalytic mechanism of a MYST family histone acetyltransferase. Biochemistry 2007 Jan 23 6
17 17368826 Notch1 intracellular domain suppresses APP intracellular domain-Tip60-Fe65 complex mediated signaling through physical interaction. Biochim Biophys Acta 2007 Jun 1
18 17551969 Tip60 modulates PLAGL2-mediated transactivation by acetylation. J Cell Biochem 2008 Feb 15 2
19 17704809 Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response. Oncogene 2008 Feb 7 2
20 17836516 Sled-type motion on the nanometer scale: determination of dissipation and cohesive energies of c60. Science 1994 Dec 23 1
21 17923702 DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity. Mol Cell Biol 2007 Dec 2
22 18042635 Epigenetic alteration of the donor cells does not recapitulate the reprogramming of DNA methylation in cloned embryos. Reproduction 2007 Dec 1
23 18263878 Tip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathway. J Biol Chem 2008 Apr 11 1
24 18285460 Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage. Mol Cell Biol 2008 Apr 1
25 18458078 Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance. J Biol Chem 2008 Jun 27 5
26 19048121 Phorbol ester enhances KAI1 transcription by recruiting Tip60/Pontin complexes. Neoplasia 2008 Dec 1
27 19114310 Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. Bioorg Med Chem 2009 Feb 1 2
28 19150978 PML3 Orchestrates the Nuclear Dynamics and Function of TIP60. J Biol Chem 2009 Mar 27 1
29 19303850 Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell 2009 Mar 20 2
30 19356627 Expression of functional metallothionein isoforms in papillary thyroid cancer. Mol Cell Endocrinol 2009 Apr 10 2
31 19783983 Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nat Cell Biol 2009 Nov 4
32 19800870 UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity. Biochem Biophys Res Commun 2009 Dec 18 2
33 20144237 Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation. Mol Cancer 2010 Feb 9 2
34 20159953 Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase. Genes Dev 2010 Feb 15 1
35 20160506 Tip60: connecting chromatin to DNA damage signaling. Cell Cycle 2010 Mar 1 4
36 20351180 The SANT domain of p400 ATPase represses acetyltransferase activity and coactivator function of TIP60 in basal p21 gene expression. Mol Cell Biol 2010 Jun 1
37 20874841 Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells. Cancer Sci 2010 Dec 1
38 21157427 Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin. EMBO J 2011 Feb 2 1
39 21284845 The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting. Neural Dev 2011 Feb 1 2
40 21320693 Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest. Cell Host Microbe 2011 Feb 17 1
41 21463657 TRIM29 negatively regulates p53 via inhibition of Tip60. Biochim Biophys Acta 2011 Jun 1
42 21555914 SRSF2 is required for sodium butyrate-mediated p21(WAF1) induction and premature senescence in human lung carcinoma cell lines. Cell Cycle 2011 Jun 15 1
43 21869962 Measuring Si-C60 chemical forces via single molecule spectroscopy. Chem Commun (Camb) 2011 Oct 14 2
44 22100137 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. Eur J Med Chem 2012 Jan 3
45 22159227 Activation of a Tip60/E2F1/ERCC1 network in human lung adenocarcinoma cells exposed to cisplatin. Carcinogenesis 2012 Feb 4
46 22249179 New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor. J Biol Chem 2012 Mar 2 4
47 22448206 Endoplasmic Reticulum (ER) Stress Enhances Tip60 (A Histone Acetyltransferase) Binding to the Concanavalin A. Open Biochem J 2012 2
48 22470428 Function of the active site lysine autoacetylation in Tip60 catalysis. PLoS One 2012 6
49 22586264 SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60. Mol Cell Biol 2012 Jul 6
50 22749149 Mechanistic links between ATM and histone methylation codes during DNA repair. Prog Mol Biol Transl Sci 2012 2