Title : Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation.

Pub. Date : 2010 Feb 9

PMID : 20144237






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that pentamidine repressed the activity of Tip60 acetyltransferase which is known to acetylate histone H2A and that knockdown of Tip60 by siRNA reduced HR activity. Pentamidine lysine acetyltransferase 5 Homo sapiens
2 We found that pentamidine repressed the activity of Tip60 acetyltransferase which is known to acetylate histone H2A and that knockdown of Tip60 by siRNA reduced HR activity. Pentamidine lysine acetyltransferase 5 Homo sapiens