cell division cycle 20 ; Homo sapiens






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1 9736712 Mad2 transiently associates with an APC/p55Cdc complex during mitosis. Proc Natl Acad Sci U S A 1998 Sep 15 1
2 10203756 Separating sister chromatids. Trends Biochem Sci 1999 Mar 1
3 10799291 Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint. Biochem Biophys Res Commun 2000 May 10 1
4 11030144 p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase. Oncogene 2000 Sep 21 1
5 12835721 Arsenic trioxide-induced mitotic arrest and apoptosis in acute promyelocytic leukemia cells. Leukemia 2003 Jul 1
6 14583462 Induction of C-anaphase and diplochromosome through dysregulation of spindle assembly checkpoint by sodium arsenite in human fibroblasts. Cancer Res 2003 Oct 15 1
7 14607335 p55CDC/hCDC20 mutant induces mitotic catastrophe by inhibiting the MAD2-dependent spindle checkpoint activity in tumor cells. Cancer Lett 2003 Nov 25 2
8 16138009 Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy. Cell Cycle 2005 Oct 3
9 16497171 A new Mad2-interacting domain of Cdc20 is critical for the function of Mad2-Cdc20 complex in the spindle assembly checkpoint. Biochem J 2006 Jun 1 2
10 16600213 Spindle checkpoint function requires Mad2-dependent Cdc20 binding to the Mad3 homology domain of BubR1. Exp Cell Res 2006 Jun 10 1
11 16648845 Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C. Nat Cell Biol 2006 Jun 1
12 16795040 Effects of histone deacetylase inhibitors on p55CDC/Cdc20 expression in HT29 cell line. J Cell Biochem 2006 Nov 1 11
13 17406033 Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic. Mol Cancer Ther 2007 Apr 1
14 17915194 KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells. Biochem Pharmacol 2008 Jan 15 3
15 18630511 Targeting of CDC20 via small interfering RNA causes enhancement of the cytotoxicity of chemoradiation. Anticancer Res 2008 May-Jun 1
16 18942872 Thermal behavior of H-aggregate in a mixed Langmuir-Blodgett film of merocyanine dye, arachidic acid, and n-octadecane ternary system investigated by UV-visible and IR absorption spectroscopy. J Phys Chem B 2008 Nov 13 1
17 19144818 Mitotic exit in the absence of separase activity. Mol Biol Cell 2009 Mar 1
18 19397590 Arsenic trioxide suppresses paclitaxel-induced mitotic arrest. Cell Prolif 2009 Jun 2
19 19708210 Thermal behavior of J-aggregates in a Langmuir-Blodgett film of pure merocyanine dye investigated by UV-visible and IR absorption spectroscopy. J Phys Chem B 2009 Mar 5 1
20 19781537 Synergistic mitosis-arresting effects of arsenic trioxide and paclitaxel on human malignant lymphocytes. Chem Biol Interact 2010 Jan 5 2
21 20054826 Cdc20 proteolysis requires p38 MAPK signaling and Cdh1-independent APC/C ubiquitination during spindle assembly checkpoint activation by cadmium. J Cell Physiol 2010 May 8
22 20081372 Requirement for proteolysis in spindle assembly checkpoint silencing. Cell Cycle 2010 Feb 1 1
23 20951947 Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell 2010 Oct 19 2
24 21042722 Novel medicinal mushroom blend suppresses growth and invasiveness of human breast cancer cells. Int J Oncol 2010 Dec 1
25 21441410 Caspase-3-dependent mitotic checkpoint inactivation by the small-molecule inducers of mitotic slippage SU6656 and geraldol. Mol Cancer Ther 2011 May 4
26 21575600 CHFR binds to and regulates MAD2 in the spindle checkpoint through its cysteine-rich domain. Biochem Biophys Res Commun 2011 Jun 10 2
27 21598039 Shogaols at proapoptotic concentrations induce G(2)/M arrest and aberrant mitotic cell death associated with tubulin aggregation. Apoptosis 2011 Aug 1
28 21853124 Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia. PLoS One 2011 1
29 22033405 Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA. Biochem Biophys Res Commun 2011 Nov 18 3
30 22086178 Cdc20 mediates D-box-dependent degradation of Sp100. Biochem Biophys Res Commun 2011 Dec 2 1
31 22475564 Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression. J Hematol Oncol 2012 Apr 4 1
32 22479587 NAHA, a novel hydroxamic acid-derivative, inhibits growth and angiogenesis of breast cancer in vitro and in vivo. PLoS One 2012 1
33 23185555 Induction of tumor cell death through targeting tubulin and evoking dysregulation of cell cycle regulatory proteins by multifunctional cinnamaldehydes. PLoS One 2012 1
34 23643811 APC/C(Cdh1)-dependent degradation of Cdc20 requires a phosphorylation on CRY-box by Polo-like kinase-1 during somatic cell cycle. Biochem Biophys Res Commun 2013 Jun 21 1
35 24621501 Phospho-Bcl-xL(Ser62) influences spindle assembly and chromosome segregation during mitosis. Cell Cycle 2014 2
36 24995417 Withaferin A modulates the Spindle assembly checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines. Biochem Pharmacol 2014 Sep 1 2
37 25156254 Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. Nature 2014 Oct 30 5
38 25368385 Deregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome. Mol Cell Biol 2015 Jan 2
39 25490258 Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome. J Mol Biol 2015 Apr 24 2
40 25505175 The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis. J Biol Chem 2015 Jan 23 1
41 25833949 EDD, a ubiquitin-protein ligase of the N-end rule pathway, associates with spindle assembly checkpoint components and regulates the mitotic response to nocodazole. J Biol Chem 2015 May 15 1
42 26061684 Alterations of the spindle checkpoint pathway in clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas. Int J Cancer 2015 Dec 1 2
43 26811472 Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation. Proc Natl Acad Sci U S A 2016 Feb 9 1
44 26912231 The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation. Nat Commun 2016 Feb 25 1
45 27120157 Molecular mechanism of APC/C activation by mitotic phosphorylation. Nature 2016 May 12 1
46 27198228 Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2. Genes Dev 2016 May 15 1
47 27626499 Rottlerin inhibits cell growth and invasion via down-regulation of Cdc20 in glioma cells. Oncotarget 2016 Oct 25 10
48 27633058 Silencing of CDC20 suppresses metastatic castration-resistant prostate cancer growth and enhances chemosensitivity to docetaxel. Int J Oncol 2016 Oct 1
49 28017606 Generation of a Spindle Checkpoint Arrest from Synthetic Signaling Assemblies. Curr Biol 2017 Jan 9 1
50 28045167 CDC20siRNA and paclitaxel co-loaded nanometric liposomes of a nipecotic acid-derived cationic amphiphile inhibit xenografted neuroblastoma. Nanoscale 2017 Jan 19 12