Title : Arsenic trioxide suppresses paclitaxel-induced mitotic arrest.

Pub. Date : 2009 Jun

PMID : 19397590






2 Functional Relationships(s)
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1 Western blot analysis showed that As(2)O(3) significantly blocked phosphorylation of BubR1, Cdc20, and Cdc27 in cells treated with paclitaxel, suggesting that arsenic compromised the activation of the spindle checkpoint. (2)o(3) cell division cycle 20 Homo sapiens
2 Western blot analysis showed that As(2)O(3) significantly blocked phosphorylation of BubR1, Cdc20, and Cdc27 in cells treated with paclitaxel, suggesting that arsenic compromised the activation of the spindle checkpoint. Paclitaxel cell division cycle 20 Homo sapiens