Title : Arsenic trioxide-induced mitotic arrest and apoptosis in acute promyelocytic leukemia cells.

Pub. Date : 2003 Jul

PMID : 12835721






1 Functional Relationships(s)
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1 (3) 1.5 mM caffeine that relieves cells from G(2)/M arrest also inhibits As(2)O(3)-induced Deltavarphi(m) collapse and apoptosis, (4) 1.0 micro M As(2)O(3) increases the expression of both cyclin B(1) and hCDC20 whereas it inhibits Tyr15 phosphorylation of p34(cdc2). Caffeine cell division cycle 20 Homo sapiens