lysophosphatidic acid receptor 1 ; Mus musculus






149 Article(s)
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51 22911670 Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer. J Natl Cancer Inst 2012 Sep 5 1
52 23251428 Protection of neuroblastoma Neuro2A cells from hypoxia-induced apoptosis by cyclic phosphatidic acid (cPA). PLoS One 2012 1
53 23318243 Involvement of LPA1 receptor signaling in cerebral ischemia-induced neuropathic pain. Neuroscience 2013 Apr 3 1
54 23322166 LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation. FASEB J 2013 May 3
55 23478264 Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostasis and wound closure. Mol Cell Biol 2013 May 1
56 23666827 Necessity of lysophosphatidic acid receptor 1 for development of arthritis. Arthritis Rheum 2013 Aug 5
57 23775489 Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors. Brain Struct Funct 2014 Sep 8
58 23909436 Downregulation of activation factors of endothelia and fibroblasts via lysophosphatidic acid signaling in a mouse lung cancer LL/2 cell line. J Recept Signal Transduct Res 2013 Oct 2
59 24115248 Lysophosphatidic acid (LPA) and its receptor, LPA1 , influence embryonic schwann cell migration, myelination, and cell-to-axon segregation. Glia 2013 Dec 4
60 24134844 Inhibitory effects of LPA1 on cell motile activities stimulated by hydrogen peroxide and 2,3-dimethoxy-1,4-naphthoquinone in fibroblast 3T3 cells. Biochem Biophys Res Commun 2013 Nov 8 7
61 24175745 Development of lysophosphatidic acid pathway modulators as therapies for fibrosis. Future Med Chem 2013 Oct 4
62 24249637 Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase. FASEB J 2014 Feb 3
63 24251962 Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts. J Cell Mol Med 2014 Jan 3
64 24429286 Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity. J Biol Chem 2014 Mar 7 5
65 24632199 Lysophosphatidic acid receptor-5 negatively regulates cellular responses in mouse fibroblast 3T3 cells. Biochem Biophys Res Commun 2014 Apr 4 2
66 24829209 Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. EMBO J 2014 Jun 17 1
67 25078448 Application of in utero electroporation of G-protein coupled receptor (GPCR) genes, for subcellular localization of hardly identifiable GPCR in mouse cerebral cortex. Mol Cells 2014 Jul 2
68 25131845 Lysophosphatidic acid stimulates cell migration of satellite cells. A role for the sphingosine kinase/sphingosine 1-phosphate axis. FEBS J 2014 Oct 2
69 25199952 Characteristics of gintonin-mediated membrane depolarization of pacemaker activity in cultured interstitial cells of Cajal. Cell Physiol Biochem 2014 1
70 25411045 Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice. Mol Pain 2014 Nov 19 10
71 25701366 Lysophosphatidic acid receptor 1 antagonist ki16425 blunts abdominal and systemic inflammation in a mouse model of peritoneal sepsis. Transl Res 2015 Jul 7
72 25822713 Lysophosphatidic acid alters the expression profiles of angiogenic factors, cytokines, and chemokines in mouse liver sinusoidal endothelial cells. PLoS One 2015 1
73 25959255 Antifibrotic effect of lysophosphatidic acid receptors LPA1 and LPA3 antagonist on experimental murine scleroderma induced by bleomycin. Exp Dermatol 2015 Sep 1
74 26090649 The lysophosphatidic acid receptor LPA4 regulates hematopoiesis-supporting activity of bone marrow stromal cells. Sci Rep 2015 Jun 19 2
75 26180199 Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury. J Neurosci 2015 Jul 15 2
76 26248018 Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation. Am J Respir Cell Mol Biol 2016 Mar 1
77 26597701 Cross-talk between lysophosphatidic acid receptor 1 and tropomyosin receptor kinase A promotes lung epithelial cell migration. Biochim Biophys Acta 2016 Feb 4
78 26700247 Both genetic deletion and pharmacological blockade of lysophosphatidic acid LPA1 receptor results in increased alcohol consumption. Neuropharmacology 2016 Apr 11
79 26743816 Lysophosphatidic acid upregulates connective tissue growth factor expression in osteoblasts through the GPCR/PKC and PKA pathways. Int J Mol Med 2016 Feb 3
80 27082727 Lysophosphatidic Acid Signaling through the Lysophosphatidic Acid-1 Receptor Is Required for Alveolarization. Am J Respir Cell Mol Biol 2016 Jul 2
81 27178323 The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages. FASEB J 2016 Aug 1
82 27500235 The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model. Transplant Direct 2015 Oct 1
83 27738243 Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program. Proc Natl Acad Sci U S A 2016 Nov 1 1
84 27760754 Lysophosphatidic acid-induced vascular neointimal formation in mouse carotid arteries is mediated by the matricellular protein CCN1/Cyr61. Am J Physiol Cell Physiol 2016 Dec 1 2
85 27883026 Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice. Sci Rep 2016 Nov 24 3
86 27927603 Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor. Kidney Int 2017 Mar 2
87 28069828 LPA<sub>1</sub> receptor-mediated thromboxane A<sub>2</sub> release is responsible for lysophosphatidic acid-induced vascular smooth muscle contraction. FASEB J 2017 Apr 4
88 28073697 Proliferation of mouse endometrial stromal cells in culture is highly sensitive to lysophosphatidic acid signaling. Biochem Biophys Res Commun 2017 Feb 26 2
89 28111010 Blocking lysophosphatidic acid receptor 1 signaling inhibits diabetic nephropathy in db/db mice. Kidney Int 2017 Jun 4
90 28240604 Autocrine lysophosphatidic acid signaling activates β-catenin and promotes lung allograft fibrosis. J Clin Invest 2017 Apr 3 1
91 28297672 Identification of Intrinsic Axon Growth Modulators for Intact CNS Neurons after Injury. Cell Rep 2017 Mar 14 1
92 28375206 maLPA1-null mice as an endophenotype of anxious depression. Transl Psychiatry 2017 Apr 4 2
93 28460477 Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice. Oncotarget 2017 Apr 18 1
94 28472283 OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA-NF-κB pathway. Cardiovasc Res 2017 Sep 1 3
95 28765047 Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI. Biochem Biophys Res Commun 2017 Sep 23 4
96 28815598 LPA<sub>1</sub> is a key mediator of intracellular signalling and neuroprotection triggered by tetracyclic antidepressants in hippocampal neurons. J Neurochem 2017 Oct 2
97 28859883 Analgesic effects of novel lysophosphatidic acid receptor 5 antagonist AS2717638 in rodents. Neuropharmacology 2017 Nov 4
98 28928633 Glutaminase and MMP-9 Downregulation in Cortex and Hippocampus of LPA<sub>1</sub> Receptor Null Mice Correlate with Altered Dendritic Spine Plasticity. Front Mol Neurosci 2017 1
99 29128569 Lysophosphatidic Acid Receptor 1 Is Important for Intestinal Epithelial Barrier Function and Susceptibility to Colitis. Am J Pathol 2018 Feb 1
100 29217823 Lysophosphatidic acid protects against acetaminophen-induced acute liver injury. Exp Mol Med 2017 Dec 8 1