lysophosphatidic acid receptor 1 ; Mus musculus






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101 29378212 Systemic blockade of LPA<sub>1/3</sub> lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior. Neuropharmacology 2018 May 1 6
102 29480526 Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory. Addict Biol 2019 May 4
103 29719665 Effect of lysophosphatidic acid on the follicular development and the expression of lysophosphatidic acid receptor genes during in vitro culture of mouse ovary. Vet Res Forum 2018 Winter 1
104 29875659 Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson's Disease via Lysophosphatidic Acid Receptors. Front Pharmacol 2018 1
105 30053596 LPA<sub>1/3</sub> signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer. Biochim Biophys Acta Mol Cell Biol Lipids 2018 Oct 1
106 30321532 Lysophosphatidic acid and its receptor LPA<sub>1</sub> mediate carrageenan induced inflammatory pain in mice. Eur J Pharmacol 2018 Dec 15 5
107 30550929 Lysophosphatidic acid receptor type 2 activation contributes to secondary damage after spinal cord injury in mice. Brain Behav Immun 2019 Feb 2
108 30622227 HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene <i>Lpar1</i> in Neocortical Neuroblast Cells. Mol Cells 2019 Feb 28 3
109 30763641 Lysophosphatidic acid receptor 1 inhibitor, AM095, attenuates diabetic nephropathy in mice by downregulation of TLR4/NF-κB signaling and NADPH oxidase. Biochim Biophys Acta Mol Basis Dis 2019 Jun 1 5
110 30804442 Molecular mechanism of lysophosphatidic acid-induced hypertensive response. Sci Rep 2019 Feb 25 2
111 31145906 Modulation of LPA1 receptor-mediated neuronal apoptosis by Saikosaponin-d: A target involved in depression. Neuropharmacology 2019 Sep 1 4
112 31191247 Lysophosphatidic Acid and Glutamatergic Transmission. Front Mol Neurosci 2019 1
113 31194005 LPA1 receptor involvement in fibromyalgia-like pain induced by intermittent psychological stress, empathy. Neurobiol Pain 2017 Jan-Jul 4
114 31194070 Lysophosphatidic acid LPA<sub>1</sub> and LPA<sub>3</sub> receptors play roles in the maintenance of late tissue plasminogen activator-induced central poststroke pain in mice. Neurobiol Pain 2019 Jan-Jul 2
115 31233937 Lysophosphatidic acid induces interleukin-6 and CXCL15 secretion from MLO-Y4 cells through activation of the LPA<sub>1</sub> receptor and PKCθ signaling pathway. Int Immunopharmacol 2019 Sep 5
116 31244601 Effects of the LPA<sub>1</sub> Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice. Front Mol Neurosci 2019 3
117 31335323 Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4. J Clin Invest 2019 Jul 23 2
118 31429777 Lysophosphatidic acid receptor 1 (LPA<sub>1</sub>) plays critical roles in microglial activation and brain damage after transient focal cerebral ischemia. J Neuroinflammation 2019 Aug 20 1
119 31429784 Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis. Arthritis Res Ther 2019 Aug 20 3
120 31633020 LPA<sub>1/3</sub> overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction. Sci Adv 2019 Oct 1
121 31849616 Small-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells. Front Cell Neurosci 2019 2
122 32065590 Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney. J Clin Invest 2020 Mar 2 2
123 32065594 Kidney to bone via bedside to bench…and back? J Clin Invest 2020 Mar 2 3
124 32627178 Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse. Br J Pharmacol 2020 Sep 1
125 32718668 Differential anatomical and cellular expression of lysophosphatidic acid receptor 1 in adult mouse brain. Biochem Biophys Res Commun 2020 Oct 15 2
126 32824296 Lysophosphatidic Acid Receptor 1- and 3-Mediated Hyperalgesia and Hypoalgesia in Diabetic Neuropathic Pain Models in Mice. Cells 2020 Aug 16 4
127 32929779 Conditional Lpar1 gene targeting identifies cell types mediating neuropathic pain. FASEB J 2020 Jul 3
128 33035633 Inhibition of lysophosphatidic acid receptor 1 attenuates neuroinflammation via PGE2/EP2/NOX2 signalling and improves the outcome of intracerebral haemorrhage in mice. Brain Behav Immun 2021 Jan 8
129 33202644 NLRP3 Inflammasome Activation Is Involved in LPA<sub>1</sub>-Mediated Brain Injury after Transient Focal Cerebral Ischemia. Int J Mol Sci 2020 Nov 14 1
130 33220367 Expression of lysophosphatidic acid receptor 1 in the adult female mouse pituitary gland. Neurosci Lett 2021 Jan 10 3
131 33317583 Altered cleavage plane orientation with increased genomic aneuploidy produced by receptor-mediated lysophosphatidic acid (LPA) signaling in mouse cerebral cortical neural progenitor cells. Mol Brain 2020 Dec 14 1
132 33508894 Interfering with lysophosphatidic acid receptor edg2/lpa<sub>1</sub> signalling slows down disease progression in SOD1-G93A transgenic mice. Neuropathol Appl Neurobiol 2021 Dec 3
133 33794254 Cannabinoid CB<sub>1</sub> and CB<sub>2</sub> receptors differentially regulate TNF-α-induced apoptosis and LPA<sub>1</sub>-mediated pro-survival signaling in HT22 hippocampal cells. Life Sci 2021 Jul 1 5
134 33841099 Dual Role of Lysophosphatidic Acid Receptor 2 (LPA<sub>2</sub>) in Amyotrophic Lateral Sclerosis. Front Cell Neurosci 2021 2
135 34025133 Gintonin influences the morphology and motility of adult brain neurons via LPA receptors. J Ginseng Res 2021 May 1
136 34147666 Loss of lysophosphatidic acid receptor 1 in hepatocytes reduces steatosis via down-regulation of CD36. Prostaglandins Other Lipid Mediat 2021 Oct 1
137 34299412 Protective Effects of Gintonin on Reactive Oxygen Species-Induced HT22 Cell Damages: Involvement of LPA1 Receptor-BDNF-AKT Signaling Pathway. Molecules 2021 Jul 7 2
138 34302117 Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis. Oncogene 2021 Sep 2
139 34478715 LPA<sub>1</sub>-mediated PKD2 activation promotes LPA-induced tissue factor expression via the p38α and JNK2 MAPK pathways in smooth muscle cells. J Biol Chem 2021 Oct 4
140 34585475 Targeting autotaxin impacts disease advance in the SOD1-G93A mouse model of amyotrophic lateral sclerosis. Brain Pathol 2022 May 8
141 34639115 Lysophosphatidic Acid Mediates Imiquimod-Induced Psoriasis-like Symptoms by Promoting Keratinocyte Proliferation through LPAR1/ROCK2/PI3K/AKT Signaling Pathway. Int J Mol Sci 2021 Oct 5 6
142 34666785 Inhibition of lysophosphatidic acid receptor 1-3 deteriorates experimental autoimmune encephalomyelitis by inducing oxidative stress. J Neuroinflammation 2021 Oct 19 4
143 34788605 Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8<sup>+</sup> T cells. Cell Rep 2021 Nov 16 2
144 35074512 LPA<sub>6</sub>-RhoA signals regulate junctional complexes for polarity and morphology establishment of maturation stage ameloblasts. J Oral Biosci 2022 Mar 2
145 35166239 LPAR1 regulates enteric nervous system function through glial signaling and contributes to chronic intestinal pseudo-obstruction. J Clin Invest 2022 Feb 15 1
146 35385768 Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle. Matrix Biol 2022 May 1
147 35406635 Lysophosphatidic Acid Receptor 5 (LPA<sub>5</sub>) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro. Cells 2022 Mar 22 2
148 35456981 Glucagon-like Peptide-1 Secretion Is Inhibited by Lysophosphatidic Acid. Int J Mol Sci 2022 Apr 9 6
149 35538534 Inhibition of ChREBP ubiquitination via the ROS/Akt-dependent downregulation of Smurf2 contributes to lysophosphatidic acid-induced fibrosis in renal mesangial cells. J Biomed Sci 2022 May 10 1