| 1 | 19113821 | Sestrin 2 is not a reductase for cysteine sulfinic acid of peroxiredoxins. | Antioxid Redox Signal | 2009 Apr |
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| 2 | 23031795 | Mechanisms involved in alternariol-induced cell cycle arrest. | Mutat Res | 2012 Oct-Nov |
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| 3 | 23274085 | Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage. | Cell Metab | 2013 Jan 8 |
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| 4 | 23495831 | Antioxidant activity of sestrin 2 controls neuropathic pain after peripheral nerve injury. | Antioxid Redox Signal | 2013 Dec 10 |
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| 5 | 23651738 | Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction. | Toxicol Appl Pharmacol | 2013 Aug 15 |
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| 6 | 24046361 | Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD. | Dis Model Mech | 2013 Nov |
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| 7 | 24368194 | Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture. | Exp Neurol | 2014 Mar |
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| 8 | 25024286 | Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of reactive oxygen species production. | Hypertension | 2014 Oct |
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| 9 | 25040165 | Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. | FEBS J | 2014 Sep |
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| 10 | 25151220 | Resveratrol attenuates methylglyoxal-induced mitochondrial dysfunction and apoptosis by Sestrin2 induction. | Toxicol Appl Pharmacol | 2014 Oct 15 |
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| 11 | 25463278 | Role of sestrin2 in the regulation of proinflammatory signaling in macrophages. | Free Radic Biol Med | 2015 Jan |
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| 12 | 25637945 | Regulation of Toll-like receptor-mediated Sestrin2 induction by AP-1, Nrf2, and the ubiquitin-proteasome system in macrophages. | Toxicol Sci | 2015 Apr |
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| 13 | 25692450 | Upregulation of Sestrin2 expression protects against macrophage apoptosis induced by oxidized low-density lipoprotein. | DNA Cell Biol | 2015 Apr |
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| 14 | 25716320 | Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions. | J Biol Chem | 2015 Apr 10 |
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| 15 | 27337507 | SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages. | Autophagy | 2016 Aug 2 |
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| 16 | 27733322 | Oleanolic acid attenuates liver ischemia reperfusion injury by HO-1/Sesn2 signaling pathway. | Hepatobiliary Pancreat Dis Int | 2016 Oct |
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| 17 | 28209544 | Sestrin2 protects against acetaminophen-induced liver injury. | Chem Biol Interact | 2017 May 1 |
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| 18 | 28578014 | Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway. | Free Radic Biol Med | 2017 Sep |
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| 19 | 28580173 | Sesn2 gene ablation enhances susceptibility to gentamicin-induced hair cell death via modulation of AMPK/mTOR signaling. | Cell Death Discov | 2017 |
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| 20 | 28729213 | Physical exercise increases Sestrin 2 protein levels and induces autophagy in the skeletal muscle of old mice. | Exp Gerontol | 2017 Oct 15 |
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| 21 | 30048751 | Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins. | Biochim Biophys Acta Mol Basis Dis | 2018 Oct |
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| 22 | 30139658 | RCAN1 is a marker of oxidative stress, induced in acute pancreatitis. | Pancreatology | 2018 Oct |
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| 23 | 30957679 | Cigarette smoke exposure induces ROS-mediated autophagy by regulating sestrin, AMPK, and mTOR level in mice. | Redox Rep | 2019 Dec |
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| 24 | 31026186 | Cardioprotective roles of sestrin 1 and sestrin 2 against doxorubicin cardiotoxicity. | Am J Physiol Heart Circ Physiol | 2019 Jul 1 |
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| 25 | 31054940 | The interaction of Hemin and Sestrin2 modulates oxidative stress and colon tumor growth. | Toxicol Appl Pharmacol | 2019 Jul 1 |
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| 26 | 31323261 | Protective effect of sestrin2 against iron overload and ferroptosis-induced liver injury. | Toxicol Appl Pharmacol | 2019 Sep 15 |
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| 27 | 31454784 | Effect of exercise and butyrate supplementation on microbiota composition and lipid metabolism. | J Endocrinol | 2019 Nov |
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| 28 | 31497357 | Methionine restriction activates the integrated stress response in triple-negative breast cancer cells by a GCN2- and PERK-independent mechanism. | Am J Cancer Res | 2019 |
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| 29 | 31842349 | Loss of p53 Sensitizes Cells to Palmitic Acid-Induced Apoptosis by Reactive Oxygen Species Accumulation. | Int J Mol Sci | 2019 Dec 12 |
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| 30 | 31875479 | ATF4-Mediated Upregulation of REDD1 and Sestrin2 Suppresses mTORC1 Activity during Prolonged Leucine Deprivation. | J Nutr | 2020 May 1 |
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| 31 | 31958198 | Sestrin2 alleviates palmitate-induced endoplasmic reticulum stress, apoptosis, and defective invasion of human trophoblast cells. | Am J Reprod Immunol | 2020 Apr |
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| 32 | 32234722 | Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet-Induced Obese Mice. | Diabetes | 2020 Jun |
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| 33 | 32363721 | Sestrin 2 attenuates sepsis-associated encephalopathy through the promotion of autophagy in hippocampal neurons. | J Cell Mol Med | 2020 Jun |
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| 34 | 32528056 | Sestrin2 inhibits YAP activation and negatively regulates corneal epithelial cell proliferation. | Exp Mol Med | 2020 Jun |
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| 35 | 32863202 | Substrate metabolism regulated by Sestrin2-mTORC1 alleviates pressure overload-induced cardiac hypertrophy in aged heart. | Redox Biol | 2020 Sep |
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| 36 | 33316744 | Sestrin2 maintains OXPHOS integrity to modulate cardiac substrate metabolism during ischemia and reperfusion. | Redox Biol | 2021 Jan |
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| 37 | 33581276 | Sestrin2 is an endogenous antioxidant that improves contractile function in the heart during exposure to ischemia and reperfusion stress. | Free Radic Biol Med | 2021 Mar |
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| 38 | 34045438 | Cyst(e)ine in nutrition formulation promotes colon cancer growth and chemoresistance by activating mTORC1 and scavenging ROS. | Signal Transduct Target Ther | 2021 May 28 |
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| 39 | 34107585 | [Protective effect of baicalein on high fat-induced hepatocytes oxidative damage]. | Zhonghua Gan Zang Bing Za Zhi | 2021 May 20 |
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| 40 | 34126555 | The involvement of Sestrin2 in the effect of IGF-I and leucine on mTROC1 activity in C2C12 and L6 myocytes. | Growth Horm IGF Res | 2021 Aug |
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| 41 | 34405320 | Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy. | Cell Biol Toxicol | 2021 Aug 17 |
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| 42 | 34482365 | Sestrin2 protects dendrite cells against ferroptosis induced by sepsis. | Cell Death Dis | 2021 Sep 4 |
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| 43 | 34688462 | Effects of chitooligosaccharide-zinc on the ovarian function of mice with premature ovarian failure via the SESN2/NRF2 signaling pathway. | Chin J Nat Med | 2021 Oct |
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| 44 | 34797495 | Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages. | Arch Pharm Res | 2022 Jan |
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| 45 | 34867324 | Knockout of AMPKα2 Blocked the Protection of Sestrin2 Overexpression Against Cardiac Hypertrophy Induced by Pressure Overload. | Front Pharmacol | 2021 |
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| 46 | 34995401 | Sestrin2 ablation attenuates the exercise-induced browning of white adipose tissue in C57BL/6J mice. | Acta Physiol (Oxf) | 2022 Mar |
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| 47 | 35348190 | 2,3,4',5‑Tetrahydroxystilbene‑2‑O‑β‑D‑glucoside ameliorates gentamicin‑induced ototoxicity by modulating autophagy via Sesn2/AMPK/mTOR signaling. | Int J Mol Med | 2022 May |
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| 48 | 35452917 | Cardiac SIRT1 ameliorates doxorubicin-induced cardiotoxicity by targeting sestrin 2. | Redox Biol | 2022 Jun |
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| 49 | 35597502 | Specific amino acids regulate Sestrin2 mRNA and protein levels in an ATF4-dependent manner in C2C12 myocytes. | Biochim Biophys Acta Gen Subj | 2022 Sep |
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