growth differentiation factor 9 ; Homo sapiens






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1 8429021 GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines. J Biol Chem 1993 Feb 15 3
2 10443672 Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early folliculogenesis. J Clin Endocrinol Metab 1999 Aug 1
3 12050262 Growth differentiation factor-9 inhibits 3'5'-adenosine monophosphate-stimulated steroidogenesis in human granulosa and theca cells. J Clin Endocrinol Metab 2002 Jun 8
4 12135884 Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9. Biol Reprod 2002 Aug 1
5 12574210 Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells. J Clin Endocrinol Metab 2003 Feb 1
6 16740654 Growth differentiation factor 9 is antiapoptotic during follicular development from preantral to early antral stage. Mol Endocrinol 2006 Oct 2
7 17156781 Growth differentiating factor-9 mutations may be associated with premature ovarian failure. Fertil Steril 2007 Jan 2
8 17482612 Analyses of GDF9 mutation in 100 Chinese women with premature ovarian failure. Fertil Steril 2007 Nov 2
9 18162287 Characterization of recombinant human growth differentiation factor-9 signaling in ovarian granulosa cells. Mol Cell Endocrinol 2008 Feb 13 3
10 19366876 Effects of growth differentiation factor 9 on cell cycle regulators and ERK42/44 in human granulosa cell proliferation. Am J Physiol Endocrinol Metab 2009 Jun 1
11 19389798 Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6. J Leukoc Biol 2009 Jul 1
12 20458753 GDF-9 promotes the growth of prostate cancer cells by protecting them from apoptosis. J Cell Physiol 2010 Nov 1
13 20660033 Growth differentiation factor 9 reverses activin A suppression of steroidogenic acute regulatory protein expression and progesterone production in human granulosa-lutein cells. J Clin Endocrinol Metab 2010 Oct 3
14 20937357 The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: characterization of the purified untagged processed mature region. Mol Cell Endocrinol 2011 Jan 30 2
15 21496799 Influence of follicular fluid GDF9 and BMP15 on embryo quality. Fertil Steril 2011 Jun 1
16 22234469 Activation of latent human GDF9 by a single residue change (Gly 391 Arg) in the mature domain. Endocrinology 2012 Mar 4
17 22759380 Heparan sulfate proteoglycans regulate responses to oocyte paracrine signals in ovarian follicle morphogenesis. Endocrinology 2012 Sep 8
18 23567549 Granulosa cell tumor mutant FOXL2C134W suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cells. Mol Cell Endocrinol 2013 Jun 15 1
19 23980176 Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes. Proc Natl Acad Sci U S A 2013 Sep 24 1
20 24313324 Effects of growth differentiation factor 9 and bone morphogenetic protein 15 on the in vitro maturation of porcine oocytes. Reprod Domest Anim 2014 Apr 2
21 24711211 CYP51A1 induced by growth differentiation factor 9 and follicle-stimulating hormone in granulosa cells is a possible predictor for unfertilization. Reprod Sci 2015 Mar 2
22 24985063 Mouse GDF9 decreases KITL gene expression in human granulosa cells. Endocrine 2015 Mar 1
23 25047539 Granulosa cells and retinoic acid co-treatment enrich potential germ cells from manually selected Oct4-EGFP expressing human embryonic stem cells. Reprod Biomed Online 2014 Sep 1
24 25049998 Rapamycin rescues the poor developmental capacity of aged porcine oocytes. Asian-Australas J Anim Sci 2014 May 1
25 25155366 Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15. Reprod Fertil Dev 2016 Mar 5
26 25253739 Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities. Biol Reprod 2014 Dec 2
27 26851603 Human single follicle growth in vitro from cryopreserved ovarian tissue after slow freezing or vitrification. Hum Reprod 2016 Apr 1
28 27056417 Testicular cell-conditioned medium supports embryonic stem cell differentiation toward germ lineage and to spermatocyte- and oocyte-like cells. Theriogenology 2016 Aug 2
29 27855376 Growth Differentiation Factor-9 Promotes Fibroblast Proliferation and Migration in Keloids through the Smad2/3 Pathway. Cell Physiol Biochem 2016 1
30 28346732 Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF-9/MAPK/Smad pathway. J Biochem Mol Toxicol 2017 Aug 3
31 29043702 N-Acetylcysteine Compared to Metformin, Improves The Expression Profile of Growth Differentiation Factor-9 and Receptor Tyrosine Kinase c-Kit in The Oocytes of Patients with Polycystic Ovarian Syndrome. Int J Fertil Steril 2018 Jan 7
32 29259415 The effect of moderate to severe endometriosis on expression of growth differentiation factor-9 mRNA in human granulosa cells under controlled ovarian hyperstimulation. Reprod Med Biol 2015 Oct 1
33 30060157 Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells. Endocrinology 2018 Sep 1 2
34 30541132 Oocyte-Secreted Factors Synergize With FSH to Promote Aromatase Expression in Primary Human Cumulus Cells. J Clin Endocrinol Metab 2019 May 1 2
35 31147040 Evaluating two ovarian decellularization methods in three species. Mater Sci Eng C Mater Biol Appl 2019 Sep 2
36 31435595 Vitrification has detrimental effects on maturation, viability, and subcellular quality of oocytes post IVM in cancerous women: An experimental study. Int J Reprod Biomed 2019 Mar 1
37 31749880 Effects of paclitaxel and cisplatin on <i>in vitro</i> ovarian follicle development. Arch Med Sci 2019 Oct 4
38 31996061 Growth differentiation factor 9 inhibits vascular endothelial growth factor expression in human granulosa cells. Gynecol Endocrinol 2020 Oct 2
39 32653508 Expression patterns and oestradiol regulation of growth differentiation factor 9 in Schizothorax prenanti. Comp Biochem Physiol B Biochem Mol Biol 2020 Oct - Nov 3
40 32777912 The antioxidant icariin protects porcine oocytes from age-related damage in vitro. Anim Biosci 2021 Apr 1
41 33409275 Imperatorin Ameliorates the Aging-Associated Porcine Oocyte Meiotic Spindle Defects by Reducing Oxidative Stress and Protecting Mitochondrial Function. Front Cell Dev Biol 2020 1
42 33743504 Role of astaxanthin as an efficient antioxidant on the in vitro maturation and vitrification of porcine oocytes. Theriogenology 2021 Jun 1
43 33754040 Single-cell transcriptome dissection of the toxic impact of Di (2-ethylhexyl) phthalate on primordial follicle assembly. Theranostics 2021 1
44 33824958 Abnormal early folliculogenesis due to impeded pyruvate metabolism in mouse oocytes†. Biol Reprod 2021 Jul 2 1
45 33826978 Effects of selected hormones and their combination on progesterone and estradiol production and proliferation of feline granulosa cells cultured in vitro. Theriogenology 2021 Jul 1 2
46 33920315 Melatonin Restores the Developmental Competence of Heat Stressed Porcine Oocytes, and Alters the Expression of Genes Related to Oocyte Maturation. Animals (Basel) 2021 Apr 10 1
47 34164502 Human dermal fibroblasts support the development of human primordial/primary follicles in a 3-dimensional alginate matrix culture system. Ann Transl Med 2021 May 3
48 34176817 Roles of NR5A1 and NR5A2 in the regulation of steroidogenesis by Clock gene and bone morphogenetic proteins by human granulosa cells. Endocr J 2021 Nov 29 3
49 34786903 The Effect of Different Doses of Melatonin on in Vitro Maturation of Human Follicular Fluid-Derived Oocyte-Like Cells. JBRA Assist Reprod 2022 Apr 17 1
50 35217236 Sitagliptin/metformin improves the fertilization rate and embryo quality in polycystic ovary syndrome patients through increasing the expression of GDF9 and BMP15: A new alternative to metformin (a randomized trial). J Reprod Immunol 2022 Mar 3