Title : Growth differentiation factor-9 inhibits 3'5'-adenosine monophosphate-stimulated steroidogenesis in human granulosa and theca cells.

Pub. Date : 2002 Jun

PMID : 12050262






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 GDF-9 inhibited 8-Br-cAMP-stimulated granulosa progesterone synthesis by approximately 40%, but did not affect basal progesterone production. 8-Bromo Cyclic Adenosine Monophosphate growth differentiation factor 9 Homo sapiens
2 GDF-9 inhibited 8-Br-cAMP-stimulated granulosa progesterone synthesis by approximately 40%, but did not affect basal progesterone production. Progesterone growth differentiation factor 9 Homo sapiens
3 Additionally, GDF-9 inhibited 8-Br-cAMP-stimulated expression of P450 side-chain cleavage and P450 aromatase. 8-br growth differentiation factor 9 Homo sapiens
4 Additionally, GDF-9 inhibited 8-Br-cAMP-stimulated expression of P450 side-chain cleavage and P450 aromatase. Cyclic AMP growth differentiation factor 9 Homo sapiens
5 Treatment of human thecal cells with GDF-9 blocked forskolin-stimulated progesterone, 17alpha-hydroxyprogesterone, and dehydroepiandrosterone synthesis. Colforsin growth differentiation factor 9 Homo sapiens
6 Treatment of human thecal cells with GDF-9 blocked forskolin-stimulated progesterone, 17alpha-hydroxyprogesterone, and dehydroepiandrosterone synthesis. Progesterone growth differentiation factor 9 Homo sapiens
7 Treatment of human thecal cells with GDF-9 blocked forskolin-stimulated progesterone, 17alpha-hydroxyprogesterone, and dehydroepiandrosterone synthesis. 17-alpha-Hydroxyprogesterone growth differentiation factor 9 Homo sapiens
8 Treatment of human thecal cells with GDF-9 blocked forskolin-stimulated progesterone, 17alpha-hydroxyprogesterone, and dehydroepiandrosterone synthesis. Dehydroepiandrosterone growth differentiation factor 9 Homo sapiens