Pub. Date : 2018 Jan
PMID : 29043702
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | N-Acetylcysteine Compared to Metformin, Improves The Expression Profile of Growth Differentiation Factor-9 and Receptor Tyrosine Kinase c-Kit in The Oocytes of Patients with Polycystic Ovarian Syndrome. | Acetylcysteine | growth differentiation factor 9 | Homo sapiens |
| 2 | The aim of this study was to investigate the effects of metformin (MET), N-acetylcysteine (NAC) and their combination on the hormonal levels and expression profile of GDF-9, BMP-15 and c-kit, as hallmarks of oocyte quality, in PCOS patients. | Metformin | growth differentiation factor 9 | Homo sapiens |
| 3 | The aim of this study was to investigate the effects of metformin (MET), N-acetylcysteine (NAC) and their combination on the hormonal levels and expression profile of GDF-9, BMP-15 and c-kit, as hallmarks of oocyte quality, in PCOS patients. | Acetylcysteine | growth differentiation factor 9 | Homo sapiens |
| 4 | The aim of this study was to investigate the effects of metformin (MET), N-acetylcysteine (NAC) and their combination on the hormonal levels and expression profile of GDF-9, BMP-15 and c-kit, as hallmarks of oocyte quality, in PCOS patients. | Acetylcysteine | growth differentiation factor 9 | Homo sapiens |
| 5 | MATERIALS AND METHODS: This prospective randomized, double-blind, placebo controlled trial aims to study the effects of MET, NAC and their combination (MET+NAC) on expression of GDF-9, BMP-15 and c-kit mRNA in oocytes [10 at the germinal vesicle (GV) stage, 10 at the MI stage, and 10 at the MII stage from per group] derived following ovulation induction in PCOS. | Acetylcysteine | growth differentiation factor 9 | Homo sapiens |
| 6 | MATERIALS AND METHODS: This prospective randomized, double-blind, placebo controlled trial aims to study the effects of MET, NAC and their combination (MET+NAC) on expression of GDF-9, BMP-15 and c-kit mRNA in oocytes [10 at the germinal vesicle (GV) stage, 10 at the MI stage, and 10 at the MII stage from per group] derived following ovulation induction in PCOS. | Acetylcysteine | growth differentiation factor 9 | Homo sapiens |
| 7 | The GDF-9 expression in unfertilized mature oocytes were significantly higher in the NAC group compared to the other groups (P<0.001). | Acetylcysteine | growth differentiation factor 9 | Homo sapiens |