apoptosis-inducing factor, mitochondrion-associated 1 ; Mus musculus






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1 6977478 Anti-self receptors. V. Properties of a mouse serum factor that blocks autorosetting receptors on lymphocytes. Immunology 1982 Feb 2
2 9598989 Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition. FEBS Lett 1998 Apr 10 4
3 12022952 Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. Biochimie 2002 Feb-Mar 3
4 12734434 Flavopiridol induces mitochondrial-mediated apoptosis in murine glioma GL261 cells via release of cytochrome c and apoptosis inducing factor. Cell Cycle 2003 May-Jun 1
5 12846982 Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease. Ann N Y Acad Sci 2003 Jun 1
6 14580681 Caspase-independent apoptosis induced by evening primrose extract in Ehrlich ascites tumor cells. Cancer Lett 2003 Nov 10 2
7 14980205 Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3. Neuron 2004 Feb 19 3
8 15491640 Increased mutation in mice genetically predisposed to oxidative damage in the brain. Mutat Res 2004 Nov 22 2
9 15526035 AIF deficiency compromises oxidative phosphorylation. EMBO J 2004 Nov 24 2
10 15590628 Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J Biol Chem 2005 Feb 25 7
11 15703386 Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. J Neurosci 2005 Feb 9 2
12 15953563 Suppressive effect of AIF, a water extract from three herbs, on collagen-induced arthritis in mice. Int Immunopharmacol 2005 Aug 1
13 16001080 AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells. EMBO J 2005 Aug 3 7
14 16156740 Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells. J Neurochem 2005 Sep 2
15 16188235 Inhibition by [corrected] ursolic acid of [corrected] calcium-induced mitochondrial permeability transition and release of two proapoptotic proteins. Biochem Biophys Res Commun 2005 Nov 11 1
16 16267234 Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. J Neurosci 2005 Nov 2 7
17 16776830 Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens. BMC Neurosci 2006 Jun 15 5
18 16860906 The neuroprotective role of attractin in neurodegeneration. Neurobiol Aging 2007 Sep 2
19 16896059 Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury. Toxicol Sci 2006 Nov 4
20 17150307 Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo. Neuroscience 2007 Feb 9 3
21 17169330 Toxic effects of cobalt in primary cultures of mouse astrocytes. Similarities with hypoxia and role of HIF-1alpha. Biochem Pharmacol 2007 Mar 1 2
22 17267093 Apoptosis-inducing factor: a matter of neuron life and death. Prog Neurobiol 2007 Feb 3
23 17318368 Enhancement of ajoene-induced apoptosis by conjugated linoleic acid in 3T3-L1 adipocytes. Apoptosis 2007 Jun 1
24 17617569 Apoptosis-inducing factor regulates death in peripheral T cells. J Immunol 2007 Jul 15 2
25 17887970 Hierarchical recruitment by AMPA but not staurosporine of pro-apoptotic mitochondrial signaling in cultured cortical neurons: evidence for caspase-dependent/independent cross-talk. J Neurochem 2007 Dec 2
26 18167347 Redox-dependent changes in molecular properties of mitochondrial apoptosis-inducing factor. J Biol Chem 2008 Feb 29 6
27 18435715 Protection by bicyclol derivatives against acetaminophen-induced acute liver failure in mice and its active mechanism. Liver Int 2008 Nov 1
28 18497877 HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. J Clin Invest 2008 Jun 3
29 18762247 Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells. Free Radic Biol Med 2008 Nov 15 11
30 19002586 In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway. Apoptosis 2008 Dec 1
31 19090913 Melatonin alters cell death processes in response to age-related oxidative stress in the brain of senescence-accelerated mice. J Pineal Res 2009 Jan 1
32 19544448 Low oxygen enhances primitive and definitive neural stem cell colony formation by inhibiting distinct cell death pathways. Stem Cells 2009 Aug 2
33 19699182 Proteasome inhibitors prevent cisplatin-induced mitochondrial release of apoptosis-inducing factor and markedly ameliorate cisplatin nephrotoxicity. Biochem Pharmacol 2010 Jan 15 14
34 19703935 Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells. Mutagenesis 2009 Nov 1
35 19836443 Modulating expression of brain heat shock proteins by estrogen in ovariectomized mice model of aging. Exp Gerontol 2010 May 1
36 19863494 Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release. ASN Neuro 2009 Nov 18 2
37 20012353 Inhibition of mammary tumor growth by estrogens: is there a specific role for estrogen receptors alpha and beta? Breast Cancer Res Treat 2010 Oct 2
38 20850531 Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: evidence in Parkinson's disease patients. Neurobiol Dis 2011 Jan 1
39 21387140 Mitochondria to nucleus translocation of AIF in mice lacking Hsp70 during ischemia/reperfusion. Basic Res Cardiol 2011 May 6
40 21571045 Caffeic acid phenethyl ester prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration. Neuroscience 2011 Aug 11 4
41 21572097 Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity. Toxicol Sci 2011 Aug 3
42 21651957 Neuroprotective effect of cyanidin-3-O-glucoside anthocyanin in mice with focal cerebral ischemia. Neurosci Lett 2011 Aug 18 3
43 22043283 Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson's diseases. PLoS One 2011 3
44 22057010 Activation of mitochondrial μ-calpain increases AIF cleavage in cardiac mitochondria during ischemia-reperfusion. Biochem Biophys Res Commun 2011 Dec 2 3
45 22076146 Apoptosis-inducing factor regulates skeletal muscle progenitor cell number and muscle phenotype. PLoS One 2011 2
46 22146192 Release of mitochondrial apoptogenic factors and cell death are mediated by CK2 and NADPH oxidase. J Cereb Blood Flow Metab 2012 Apr 2
47 22194654 Visible light may directly induce nuclear DNA damage triggering the death pathway in RGC-5 cells. Mol Vis 2011 1
48 22201945 Temporal and spatial expression of AIF in the mouse uterus during early pregnancy. Front Biosci (Elite Ed) 2012 Jan 1 3
49 22486217 Dopaminochrome induces caspase-independent apoptosis in the mesencephalic cell line, MN9D. J Neurochem 2012 Jul 5
50 22534064 Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia. Mol Neurodegener 2012 Apr 25 1