Title : Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: evidence in Parkinson's disease patients.

Pub. Date : 2011 Jan

PMID : 20850531






1 Functional Relationships(s)
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1 In vivo chemical inhibition of caspases and poly(ADP-ribose)polymerase-1, an upstream regulator of AIF release and calpain, proved the central role of the AIF-dependent pathway in LPS-induced nigral DA cell death. amsonic acid apoptosis-inducing factor, mitochondrion-associated 1 Mus musculus