apoptosis-inducing factor, mitochondrion-associated 1 ; Mus musculus






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51 22574158 Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. PLoS One 2012 9
52 22865232 AIF depletion provides neuroprotection through a preconditioning effect. Apoptosis 2012 Oct 4
53 23065091 Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling. Apoptosis 2012 Dec 6
54 23246553 AIF, reactive oxygen species, and neurodegeneration: a "complex" problem. Neurochem Int 2013 Apr 5
55 23272231 Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death. PLoS One 2012 1
56 23685150 Cardioprotection by modulation of mitochondrial respiration during ischemia-reperfusion: role of apoptosis-inducing factor. Biochem Biophys Res Commun 2013 Jun 14 1
57 24080830 DNA damage and cell cycle arrest induced by protoporphyrin IX in sarcoma 180 cells. Cell Physiol Biochem 2013 1
58 24434516 Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress. Cell Death Dis 2014 Jan 16 1
59 24476502 PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury. J Neurotrauma 2014 Apr 15 2
60 25052090 PARP1-mediated necrosis is dependent on parallel JNK and Ca²⁺/calpain pathways. J Cell Sci 2014 Oct 1 1
61 25101006 A deficiency of apoptosis inducing factor (AIF) in Harlequin mouse heart mitochondria paradoxically reduces ROS generation during ischemia-reperfusion. Front Physiol 2014 3
62 25370781 mReg2 inhibits nuclear entry of apoptosis-inducing factor in mouse insulinoma cells. Growth Factors 2015 Feb 3
63 25429088 Diosgenin stimulates rat TM4 cell proliferation through activating plasma membrane translocation and transcriptional activity of estrogen receptors. Biol Reprod 2015 Jan 2
64 25603607 [Effects of bisphenol A exposure during lactation on testicular mitochondria in male mouse offspring]. Wei Sheng Yan Jiu 2014 Nov 1
65 25870767 Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. PeerJ 2015 1
66 26031348 N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis. J Neurochem 2015 Sep 1
67 26142340 Berberine Induces Cell Apoptosis through Cytochrome C/Apoptotic Protease-Activating Factor 1/Caspase-3 and Apoptosis Inducing Factor Pathway in Mouse Insulinoma Cells. Chin J Integr Med 2019 Nov 3
68 26148186 A Potent Inhibitor of Phosphoinositide 3-Kinase (PI3K) and Mitogen Activated Protein (MAP) Kinase Signalling, Quercetin (3, 3', 4', 5, 7-Pentahydroxyflavone) Promotes Cell Death in Ultraviolet (UV)-B-Irradiated B16F10 Melanoma Cells. PLoS One 2015 2
69 26197224 Neuroprotective effect of astaxanthin against glutamate-induced cytotoxicity in HT22 cells: Involvement of the Akt/GSK-3β pathway. Neuroscience 2015 Sep 10 1
70 26535916 Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD(+)/H Binding to Mitochondrial Apoptosis-Inducing Factor. Biochemistry 2015 Dec 1 3
71 26547530 Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer. Phytomedicine 2015 Nov 15 2
72 26656745 Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model. Exp Gerontol 2016 Mar 1
73 26683770 Deoxypodophyllotoxin triggers parthanatos in glioma cells via induction of excessive ROS. Cancer Lett 2016 Feb 28 2
74 26822084 Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis. Diabetes 2016 Apr 2
75 26854718 Pristimerin triggers AIF-dependent programmed necrosis in glioma cells via activation of JNK. Cancer Lett 2016 Apr 28 6
76 27031959 Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway. Cell Death Dis 2016 Mar 31 2
77 27339879 Caspase-1 Deficiency Alleviates Dopaminergic Neuronal Death via Inhibiting Caspase-7/AIF Pathway in MPTP/p Mouse Model of Parkinson's Disease. Mol Neurobiol 2017 Aug 3
78 28110215 Neuroprotective action of N-acetyl serotonin in oxidative stress-induced apoptosis through the activation of both TrkB/CREB/BDNF pathway and Akt/Nrf2/Antioxidant enzyme in neuronal cells. Redox Biol 2017 Apr 2
79 28666871 Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor. Biochem Biophys Res Commun 2017 Aug 26 4
80 28672809 Montelukast Induces Apoptosis-Inducing Factor-Mediated Cell Death of Lung Cancer Cells. Int J Mol Sci 2017 Jun 24 3
81 28732772 A brain-specific isoform of apoptosis-inducing factor 2 attenuates ischemia-induced oxidative stress in HT22 cells. Neurochem Int 2018 Jan 2
82 28749416 Anti-Oxidative Stress Activity Is Essential for Amanita caesarea Mediated Neuroprotection on Glutamate-Induced Apoptotic HT22 Cells and an Alzheimer's Disease Mouse Model. Int J Mol Sci 2017 Jul 27 4
83 29255269 Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Nat Immunol 2018 Feb 1
84 29323266 AIF loss deregulates hematopoiesis and reveals different adaptive metabolic responses in bone marrow cells and thymocytes. Cell Death Differ 2018 May 4
85 29441017 15, 16-Dihydrotanshinone I Inhibits Hemangiomas through Inducing Pro-apoptotic and Anti-angiogenic Mechanisms <i>in Vitro</i> and <i>in Vivo</i>. Front Pharmacol 2018 1
86 29780003 A disease-associated Aifm1 variant induces severe myopathy in knockin mice. Mol Metab 2018 Jul 2
87 30304679 Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity. Cell Rep 2018 Oct 9 1
88 30421242 Inhibition of VDAC1 Protects Against Glutamate-Induced Oxytosis and Mitochondrial Fragmentation in Hippocampal HT22 Cells. Cell Mol Neurobiol 2019 Jan 2
89 30841419 Modified Xiaoyao San ameliorates depressive-like behaviors by triggering autophagosome formation to alleviate neuronal apoptosis. Biomed Pharmacother 2019 Mar 2
90 30906210 Farrerol Ameliorates APAP-induced Hepatotoxicity via Activation of Nrf2 and Autophagy. Int J Biol Sci 2019 1
91 31174020 Doxorubicin-induced testicular damage is related to PARP-1 signaling molecules in mice. Pharmacol Rep 2019 Aug 1
92 31340214 Allicin Protects against Cisplatin-Induced Stria Vascularis Damage: Possible Relation to Inhibition of Caspase-3 and PARP-1-AIF-Mediated Apoptotic Pathways. ORL J Otorhinolaryngol Relat Spec 2019 4
93 31794795 TRPM2 ion channel is involved in the aggravation of cognitive impairment and down regulation of epilepsy threshold in pentylenetetrazole-induced kindling mice. Brain Res Bull 2020 Feb 1
94 32273547 Influence of Chronic Ethanol Consumption on Apoptosis and Autophagy Following Transient Focal Cerebral Ischemia in Male Mice. Sci Rep 2020 Apr 9 1
95 32277944 Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after hypoxia-ischemia. Neuropharmacology 2020 Jul 2
96 32480041 Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus. Mol Metab 2020 Oct 4
97 32767404 Apoptosis-inducing factor deficient mice fail to develop hepatic steatosis under high fat high fructose diet or bile duct ligation. Cell Biochem Funct 2021 Mar 1
98 33597260 Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy. Sci Transl Med 2021 Feb 17 2
99 33603830 Phenoxythiophene sulfonamide compound B355252 protects neuronal cells against glutamate-induced excitotoxicity by attenuating mitochondrial fission and the nuclear translocation of AIF. Exp Ther Med 2021 Mar 5
100 33968358 Apoptosis-Inducing Factor, Protein Expression, and Apoptosis Changes with Glutamine in Podocytes Cells Exposed with Cisplatin. Vet Med Int 2021 1