sphingomyelin synthase 1 ; Mus musculus






34 Article(s)
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1 2998367 Retinoic acid modulation of 1,25(OH)2 vitamin D3 receptors and bioresponse in bone cells: species differences between rat and mouse. Biochem Biophys Res Commun 1985 Oct 15 2
2 7815897 The immunosuppressive substance 2-chloro-2-deoxyadenosine modulates lipoprotein metabolism in a murine macrophage cell line (P388 cells). Lipids 1994 Sep 2
3 14976195 Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells. J Biol Chem 2004 Apr 30 10
4 16025460 Simultaneous activation of mouse main and accessory olfactory bulbs by odors or pheromones. J Comp Neurol 2005 Sep 5 1
5 16226406 The mouse sphingomyelin synthase 1 (SMS1) gene is alternatively spliced to yield multiple transcripts and proteins. Gene 2005 Dec 19 12
6 16508036 Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice. J Lipid Res 2006 Jun 4
7 16629332 Iron chelators: correlation between effects on Plasmodium spp. and immune functions. J Parasitol 2006 Feb 1
8 16879426 Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast. FEMS Yeast Res 2006 Aug 9
9 17049047 Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts. Biochem J 2007 Jan 15 1
10 17699729 A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells. Mol Cancer Ther 2007 Aug 3
11 21115496 Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice. J Biol Chem 2011 Feb 4 10
12 22345277 CD4+ T-cell dysfunctions through the impaired lipid rafts ameliorate concanavalin A-induced hepatitis in sphingomyelin synthase 1-knockout mice. Int Immunol 2012 May 1
13 22641779 Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice. J Physiol 2012 Aug 15 1
14 22688512 Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway. Mol Cell Biol 2012 Aug 2
15 23593476 Increased oxidative stress impairs adipose tissue function in sphingomyelin synthase 1 null mice. PLoS One 2013 7
16 26224860 Differential Muscarinic Modulation in the Olfactory Bulb. J Neurosci 2015 Jul 29 2
17 27391427 Inhibition of sphingomyelin synthase 1 affects ceramide accumulation and hydrogen peroxide-induced apoptosis in Neuro-2a cells. Neuroreport 2016 Sep 7 11
18 27788151 Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice. PLoS One 2016 2
19 27882938 Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition. Cell Death Dis 2016 Nov 24 5
20 28229459 Differential serotonergic modulation across the main and accessory olfactory bulbs. J Physiol 2017 Jun 1 8
21 28731029 Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses. Nat Commun 2017 Jul 21 2
22 29369436 Sphingomyelin in microdomains of the plasma membrane regulates amino acid-stimulated mTOR signal activation. Cell Biol Int 2018 Jul 1
23 30243987 Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1. Exp Neurol 2019 Jan 5
24 30561621 Plasma membrane sphingomyelin modulates thymocyte development by inhibiting TCR-induced apoptosis. Int Immunol 2019 Mar 28 1
25 30580239 Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor. Eur J Med Chem 2019 Feb 1 2
26 31262710 Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response. EBioMedicine 2019 Jul 1
27 31847800 Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation. Mol Med 2019 Dec 17 1
28 32088125 Discovery of 1,8-naphthyridin-2-one derivative as a potent and selective sphingomyelin synthase 2 inhibitor. Bioorg Med Chem 2020 Apr 1 1
29 33208407 Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis. Gut 2021 Oct 1
30 33545384 Effect of liver total sphingomyelin synthase deficiency on plasma lipid metabolism. Biochim Biophys Acta Mol Cell Biol Lipids 2021 May 10
31 34478523 A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency. Blood Adv 2021 Oct 26 14
32 34774525 Sphingomyelin synthases 1 and 2 exhibit phosphatidylcholine phospholipase C activity. J Biol Chem 2021 Dec 6
33 34927020 Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation. iScience 2021 Dec 17 4
34 35230716 Sphingomyelin maintains the cutaneous barrier via regulation of the STAT3 pathway. FASEB J 2022 Apr 1