| 1 | 284384 | Mechanism of interferon action: phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase. | Proc Natl Acad Sci U S A | 1979 Feb |
4 |
| 2 | 287050 | In situ phosphorylation of the alpha subunit of eukaryotic initiation factor 2 in reticulocyte lysates inhibited by heme deficiency, double-stranded RNA, oxidized glutathione, or the heme-regulated protein kinase. | Proc Natl Acad Sci U S A | 1979 May |
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| 3 | 497219 | Initiation of endogenous messenger RNA translation on hen oviduct polysomes. | Biochim Biophys Acta | 1979 Oct 25 |
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| 4 | 1346129 | Stimulation of protein synthesis in COS cells transfected with variants of the alpha-subunit of initiation factor eIF-2. | J Biol Chem | 1992 Jan 5 |
2 |
| 5 | 1347793 | The vaccinia virus K3L gene product potentiates translation by inhibiting double-stranded-RNA-activated protein kinase and phosphorylation of the alpha subunit of eukaryotic initiation factor 2. | J Virol | 1992 Apr |
1 |
| 6 | 1671834 | The substrate specificity of protein kinases which phosphorylate the alpha subunit of eukaryotic initiation factor 2. | Eur J Biochem | 1991 Feb 14 |
1 |
| 7 | 1677563 | A synthetic peptide substrate for initiation factor-2 kinases. | Biochem Biophys Res Commun | 1991 Jul 31 |
1 |
| 8 | 1696506 | Phosphorylation of protein synthesis initiation factor-2. Identification of the site in the alpha-subunit phosphorylated in reticulocyte lysates. | Biochim Biophys Acta | 1990 Aug 13 |
1 |
| 9 | 1698291 | Adenovirus inhibition of cellular protein synthesis is prevented by the drug 2-aminopurine. | Proc Natl Acad Sci U S A | 1990 Sep |
1 |
| 10 | 1701139 | Increased eIF-2 alpha expression in mitogen-activated primary T lymphocytes. | EMBO J | 1990 Dec |
1 |
| 11 | 1748310 | Synthesis of human initiation factor-2 alpha in Saccharomyces cerevisiae. | Gene | 1991 Dec 15 |
1 |
| 12 | 2555543 | Inhibition of translation in cells infected with a poliovirus 2Apro mutant correlates with phosphorylation of the alpha subunit of eucaryotic initiation factor 2. | J Virol | 1989 Dec |
1 |
| 13 | 2722851 | Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme. | J Biol Chem | 1989 Jun 5 |
4 |
| 14 | 2982850 | Kinetics of dephosphorylation of eIF-2(alpha P) and reutilization of mRNA. | J Biol Chem | 1985 Mar 10 |
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| 15 | 3377809 | The effect of ethanol on polypeptide chain initiation in reticulocyte lysates. Inhibition of recycling of initiation factor eIF-2. | Biochem Pharmacol | 1988 May 15 |
2 |
| 16 | 3456582 | Fate of reversing factor during restoration of protein synthesis by hemin or GTP in heme-deficient reticulocyte lysates. | Proc Natl Acad Sci U S A | 1986 Mar |
16 |
| 17 | 3457011 | Partial purification and characterization of phorbol ester-regulated translational inhibitor(s) in human HL-60 leukemic cells. | J Biol Chem | 1986 Apr 15 |
2 |
| 18 | 3462720 | Formation of a translational inhibitor by interaction of phospholipid with the eukaryotic initiation factor 2. | Proc Natl Acad Sci U S A | 1986 Sep |
2 |
| 19 | 3597436 | Identification of spectrin-related peptides associated with the reticulocyte heme-controlled alpha subunit of eukaryotic translational initiation factor 2 kinase and of Mr 95,000 peptide that appears to be the catalytic subunit. | J Biol Chem | 1987 Jul 15 |
1 |
| 20 | 3796608 | An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell lines. | Mol Cell Biol | 1986 Dec |
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| 21 | 3886657 | Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification. | J Biol Chem | 1985 May 10 |
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| 22 | 3926772 | The 60 S ribosomal subunit as a carrier of eukaryotic initiation factor 2 and the site of reversing factor activity during protein synthesis. | J Biol Chem | 1985 Aug 15 |
2 |
| 23 | 3941080 | Activation of hemin-regulated initiation factor-2 kinase in heat-shocked HeLa cells. | J Biol Chem | 1986 Jan 5 |
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| 24 | 6292906 | Regulation of double-stranded RNA-activated eukaryotic initiation factor 2 alpha kinase by type 2 protein phosphatase in reticulocyte lysates. | Proc Natl Acad Sci U S A | 1982 Nov |
2 |
| 25 | 6557115 | Phosphorylation of initiation factor eIF-2 alpha, binding of mRNA to 48 S complexes, and its reutilization in initiation of protein synthesis. | J Biol Chem | 1983 Dec 10 |
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| 26 | 6736041 | Effects of glucose 6-phosphate and hemin on activation of heme-regulated eIF-2 alpha kinase in gel-filtered reticulocyte lysates. | J Biol Chem | 1984 Jul 10 |
4 |
| 27 | 6940153 | Relationship between phosphorylation and activity of heme-regulated eukaryotic initiation factor 2 alpha kinase. | Proc Natl Acad Sci U S A | 1981 Feb |
2 |
| 28 | 7058326 | Polyamines inhibit the protein kinase 380--catalyzed phosphorylation of eukaryotic initiation factor 2 alpha. | Science | 1982 Jan 22 |
6 |
| 29 | 7298610 | The use of porphyrins as probes to examine the requirement for hemin in the maintenance of protein synthesis in reticulocyte lysates. | J Biol Chem | 1981 Nov 25 |
3 |
| 30 | 7556162 | Activation of the double-stranded-RNA-activated protein kinase and induction of vascular cell adhesion molecule-1 by poly (I).poly (C) in endothelial cells. | Eur J Biochem | 1995 Aug 15 |
2 |
| 31 | 7911326 | Regulation of eIF-2 alpha-subunit phosphorylation in reticulocyte lysate. | Biochemistry | 1994 May 31 |
1 |
| 32 | 8002004 | Mechanism of action of an eukaryotic initiation factor-2 (eIF-2) associated 67 kDa glycoprotein (p67) and an eIF-2 kinase (dsI). | Indian J Biochem Biophys | 1994 Aug |
2 |
| 33 | 8099443 | Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast. | Proc Natl Acad Sci U S A | 1993 May 15 |
4 |
| 34 | 8099586 | Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent, initiation factor 2 alpha-specific protein kinase. | J Biol Chem | 1993 Jun 15 |
2 |
| 35 | 8506384 | A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast. | Proc Natl Acad Sci U S A | 1993 Jun 1 |
1 |
| 36 | 8509427 | Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis. | J Biol Chem | 1993 Jun 15 |
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| 37 | 8619603 | Type 1 phosphatase inhibitors reduce the restoration of guanine nucleotide exchange activity of eukaryotic initiation factor 2B inhibited reticulocyte lysates rescued by hemin. | Arch Biochem Biophys | 1996 Mar 15 |
3 |
| 38 | 8786843 | Phosphorylation of initiation factor 2 alpha subunit and apoptosis in Ca2+ ionophore-treated cultured neuronal cells. | Neurosci Lett | 1995 Dec 15 |
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| 39 | 8798781 | Inhibition of translational initiation by activators of the glucose-regulated stress protein and heat shock protein stress response systems. Role of the interferon-inducible double-stranded RNA-activated eukaryotic initiation factor 2alpha kinase. | J Biol Chem | 1996 Oct 4 |
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| 40 | 8903508 | The eIF-2alpha kinases and the control of protein synthesis. | FASEB J | 1996 Oct |
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| 41 | 9328281 | Wheat germ initiation factor 2 (WG x eIF2) decreases the inhibition in protein synthesis and eIF2B activity of reticulocyte lysates mediated by eIF2alpha phosphorylation. | Arch Biochem Biophys | 1997 Oct 1 |
2 |
| 42 | 9637736 | An examination of the role of increased cytosolic free Ca2+ concentrations in the inhibition of mRNA translation. | Arch Biochem Biophys | 1998 Jun 15 |
2 |
| 43 | 9653178 | Depletion of intracellular Ca2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole. | Proc Natl Acad Sci U S A | 1998 Jul 7 |
2 |
| 44 | 9874252 | Heme-regulated eIF-2alpha kinase purifies as a hemoprotein. | Eur J Biochem | 1998 Dec 1 |
2 |
| 45 | 9930704 | Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. | Nature | 1999 Jan 21 |
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| 46 | 10216940 | Eukaryotic initiation factor eIF2. | Int J Biochem Cell Biol | 1999 Jan |
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| 47 | 10373514 | Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB. | Mol Cell Biol | 1999 Jul |
2 |
| 48 | 10400313 | Resistance of initiation factor 2 (eIF-2alpha) kinases to staurosporine: an approach for assaying the kinases in crude extracts. | Cell Signal | 1999 Jun |
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| 49 | 10432301 | Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2alpha. | Biochem J | 1999 Aug 15 |
7 |
| 50 | 10433359 | Identification by two-dimensional gel electrophoresis of vaccinia virus and cellular phosphoproteins modified after inducible expression of the dsRNA-activated protein kinase. | J Interferon Cytokine Res | 1999 Jun |
2 |