Pub. Date : 1998 Dec 1
PMID : 9874252
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we have examined the heme regulation directly on the homogeneous heme-regulated eIF-2alpha kinase (HRI), which is activated during heme deficiency. | Heme | eukaryotic translation initiation factor 2A | Homo sapiens |
| 2 | This HRI was an active autokinase and eIF-2alpha kinase, and its kinase activities were inhibited by submicromolar concentrations of hemin with an apparent Ki of 0.5 microM. | Hemin | eukaryotic translation initiation factor 2A | Homo sapiens |