Title : Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme.

Pub. Date : 1989 Jun 5

PMID : 2722851






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme. Disulfides eukaryotic translation initiation factor 2A Homo sapiens
2 Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme. Heme eukaryotic translation initiation factor 2A Homo sapiens
3 A similar high molecular mass form is observed when HRI is treated with 1,6-bismaleimidohexane, a double sulfhydryl cross-linker agent, and the autophosphorylation of HRI and the phosphorylation of eIF-2 alpha by HRI are greatly diminished; these effects are similar to the effects of hemin on HRI. 1,6-bismaleimidohexane eukaryotic translation initiation factor 2A Homo sapiens
4 A similar high molecular mass form is observed when HRI is treated with 1,6-bismaleimidohexane, a double sulfhydryl cross-linker agent, and the autophosphorylation of HRI and the phosphorylation of eIF-2 alpha by HRI are greatly diminished; these effects are similar to the effects of hemin on HRI. Hemin eukaryotic translation initiation factor 2A Homo sapiens