factor interacting with PAPOLA and CPSF1 ; Homo sapiens






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1 7675408 DNA-based prenatal determination of the RhEe genotype. Obstet Gynecol 1995 Oct 1
2 7833484 Rh E/e genotyping by allele-specific primer amplification. Blood 1995 Feb 1 9
3 8504984 The use of recombinant human erythropoietin to prevent carboplatin-induced anemia. Gynecol Oncol 1993 May 3
4 8969812 Effect of chronic erythropoietin administration on plasma iron in newborn lambs. Biol Neonate 1996 11
5 12660384 A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 2003 Mar 27 4
6 12842979 CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy. Blood 2003 Nov 1 3
7 14676627 The FIP1L1-PDGFRalpha kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia. Curr Opin Hematol 2004 Jan 5
8 14676628 Clinical, genetic, and therapeutic insights into systemic mast cell disease. Curr Opin Hematol 2004 Jan 1
9 14749727 Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. EMBO J 2004 Feb 11 2
10 14757533 Targeted treatment of hypereosinophilic syndromes and chronic eosinophilic leukemias with imatinib mesylate. Semin Cancer Biol 2004 Feb 2
11 14973504 Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias. Leukemia 2004 Apr 3
12 15003901 Imatinib mesylate can induce complete molecular remission in FIP1L1-PDGFR-a positive idiopathic hypereosinophilic syndrome. Haematologica 2004 Feb 1
13 15036941 Imatinib therapy for hypereosinophilic syndrome and eosinophilia-associated myeloproliferative disorders. Leuk Res 2004 May 1
14 15175999 Platelet-derived growth factor receptor inhibition to treat idiopathic hypereosinophilic syndrome. Semin Oncol 2004 Apr 6
15 15284118 FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia. Blood 2004 Nov 15 1
16 15305431 Targeted treatment of hypereosinophilic syndromes and chronic eosinophilic leukemias with imatinib mesylate. Semin Cancer Biol 2004 Aug 2
17 15339694 Soft tissue and skeletal involvement in FIP1L1-PDGFR-alpha positive chronic eosinophilic leukemia: imatinib mesylate may induce complete molecular and imaging remission. Haematologica 2004 Aug 1
18 15455302 [Complete remission of an idiopathic hypereosinophilic syndrome while using imatinib]. Dtsch Med Wochenschr 2004 Oct 1 1
19 15500716 [Identification of FIP1L1-PDGFRA fusion, and expression of signal transducer and activator of transcription 5 in hypereosinophilic syndrome]. Zhonghua Yi Xue Za Zhi 2004 Sep 17 1
20 15567248 Effects of the plant alkaloid thaliblastine on non-cross-resistant and sensitive human leukemia cells in relation with reversal of acquired anthracycline resistance. Fitoterapia 2004 Dec 1
21 15618966 Myeloid blast crisis evolving during imatinib treatment of an FIP1L1-PDGFR alpha-positive chronic myeloproliferative disease with prominent eosinophilia. Leukemia 2005 Feb 1
22 15621768 Rapid reversion of Loeffler's endocarditis by imatinib in early stage clonal hypereosinophilic syndrome. Leuk Lymphoma 2004 Dec 1
23 15700042 Early endostatin treatment inhibits metastatic seeding of murine colorectal cancer cells in the liver and their adhesion to endothelial cells. Br J Cancer 2005 Feb 28 1
24 15854548 [The activation of JAK/STAT signal pathway in hypereosinophilic syndrome and the patients therapeutic response to imatinib]. Zhonghua Yi Xue Za Zhi 2005 Feb 23 3
25 15921304 [Disorders with eosinophilia, treatment of hypereosinophilic syndrome]. Orv Hetil 2005 May 1 1
26 15937220 Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition. Genes Dev 2005 Jun 1 1
27 15995324 Systemic mastocytosis: bone marrow pathology, classification, and current therapies. Acta Haematol 2005 1
28 16030188 The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRbeta and FIP1L1-PDGFRalpha in vitro and in vivo. Blood 2005 Nov 1 1
29 16089297 FIP1L1-PDGFR alpha, a therapeutic target for the treatment of chronic eosinophilic leukemia. Verh K Acad Geneeskd Belg 2005 3
30 16344672 Idiopathic hypereosinophilic syndrome in children: report of a 7-year-old boy with FIP1L1-PDGFRA rearrangement. J Pediatr Hematol Oncol 2005 Dec 1
31 16406016 FIP1L1-PDGFRA in eosinophilic disorders: prevalence in routine clinical practice, long-term experience with imatinib therapy, and a critical review of the literature. Leuk Res 2006 Aug 2
32 16406018 Systemic mastocytosis (SM) associated with chronic eosinophilic leukemia (SM-CEL): detection of FIP1L1/PDGFRalpha, classification by WHO criteria, and response to therapy with imatinib. Leuk Res 2006 Sep 1
33 16479834 [Oncogene Fip1-likeL/PDGFRalpha as a target for imatinib in patients with hypereosinophilic syndrome and chronic eosinophilic leukemia. A novel look at pathogenesis and therapy]. Pol Arch Med Wewn 2005 May 1
34 16485879 A comprehensive review of imatinib mesylate (Gleevec) for dermatological diseases. J Drugs Dermatol 2006 Feb 1
35 16612767 Hypereosinophilic syndrome: lymphoproliferative and myeloproliferative variants. Semin Respir Crit Care Med 2006 Apr 1
36 16645167 Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant. Blood 2006 Aug 15 7
37 16682077 Activity of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, against human FIP1L1-PDGFR-alpha-expressing cells. Leuk Res 2006 Dec 2
38 16690743 Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent. Proc Natl Acad Sci U S A 2006 May 23 1
39 16754777 The FIP1L1-PDGFRA T674I mutation can be inhibited by the tyrosine kinase inhibitor AMN107 (nilotinib). Blood 2006 Jun 15 2
40 16781490 Pathogenesis, clinical features, and treatment advances in mastocytosis. Best Pract Res Clin Haematol 2006 1
41 16965435 Platelet-derived growth factor receptor-alpha-associated hypereosinophilic syndrome and lymphomatoid papulosis. Br J Dermatol 2006 Oct 1
42 17215855 FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells. Leukemia 2007 Mar 1
43 17258775 Differentiation of eosinophilic leukemia EoL-1 cells into eosinophils induced by histone deacetylase inhibitors. Life Sci 2007 Mar 6 1
44 17299092 Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia. Blood 2007 Jun 1 5
45 17440089 Molecular mechanisms underlying FIP1L1-PDGFRA-mediated myeloproliferation. Cancer Res 2007 Apr 15 2
46 17488167 Systemic mastocytosis: a concise clinical and laboratory review. Arch Pathol Lab Med 2007 May 1
47 17495975 The novel tyrosine kinase inhibitor EXEL-0862 induces apoptosis in human FIP1L1-PDGFR-alpha-expressing cells through caspase-3-mediated cleavage of Mcl-1. Leukemia 2007 Jul 3
48 17541270 Recent advances in eosinophil biology. Int Arch Allergy Immunol 2007 1
49 17541273 Mechanism for the differentiation of EoL-1 cells into eosinophils by histone deacetylase inhibitors. Int Arch Allergy Immunol 2007 4
50 17544504 Maintenance therapy with imatinib appears necessary despite molecular remission in FIP1L1-PDGFRA fusion gene positive hypereosinophilic disorder. Leuk Res 2008 Jan 2