Pub. Date : 2007 Apr 15
PMID : 17440089
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An interstitial deletion on chromosome 4q12 resulting in the formation of the FIP1L1-PDGFRA fusion protein is involved in the pathogenesis of imatinib-sensitive chronic eosinophilic leukemia. | Imatinib Mesylate | factor interacting with PAPOLA and CPSF1 | Homo sapiens |
| 2 | FIP1L1-PDGFRA induced both proliferation and differentiation of eosinophils, neutrophils, and erythrocytes in the absence of cytokines, which could be inhibited by imatinib. | Imatinib Mesylate | factor interacting with PAPOLA and CPSF1 | Homo sapiens |