Title : Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.

Pub. Date : 2006 May 23

PMID : 16690743






1 Functional Relationships(s)
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1 Instead, truncation of PDGFRalpha between two conserved tryptophan residues in the juxtamembrane (JM) domain is required for kinase activation and transforming potential of FIP1L1-PDGFRalpha. Tryptophan factor interacting with PAPOLA and CPSF1 Homo sapiens