Pub. Date : 2004 Apr
PMID : 14973504
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In FIP1L1-PDGFRA (+) CEL, palpable splenomegaly was present in 5/8 cases, serum vitamin B(12) was always markedly increased, and marrow biopsies revealed a distinctively myeloproliferative aspect. | Niacinamide | factor interacting with PAPOLA and CPSF1 | Homo sapiens |
| 2 | Imatinib induced rapid complete hematological responses in 4/4 treated FIP1L1-PDGFRA (+) cases, including one female, and complete molecular remission in 2/3 evaluable cases. | Imatinib Mesylate | factor interacting with PAPOLA and CPSF1 | Homo sapiens |
| 3 | Thus, correlating IHES/CEL genotype with phenotype, FIP1L1-PDGFRA (+) CEL emerges as a homogeneous clinicobiological entity, where imatinib can induce molecular remission. | Imatinib Mesylate | factor interacting with PAPOLA and CPSF1 | Homo sapiens |