Pub. Date : 2021
PMID : 35046793
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | peroxisome proliferator activated receptor gamma | Mus musculus |
| 2 | Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | interleukin 10 | Mus musculus |
| 3 | Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | interleukin 10 | Mus musculus |
| 4 | Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | tumor necrosis factor | Mus musculus |
| 5 | Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | tumor necrosis factor | Mus musculus |
| 6 | Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | interleukin 1 beta | Mus musculus |
| 7 | Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | interleukin 1 alpha | Mus musculus |
| 8 | The CGS21680-induced upregulation of P65 and IL-10 was abolished in macrophages upon PPARgamma knockdown. | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | interleukin 10 | Mus musculus |
| 9 | The CGS21680-induced upregulation of P65 and IL-10 was abolished in macrophages upon PPARgamma knockdown. | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | peroxisome proliferator activated receptor gamma | Mus musculus |
| 10 | The downregulation of TNF-alpha and IL-1beta by CGS21680 was less affected by PPARgamma knockdown. | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | tumor necrosis factor | Mus musculus |
| 11 | The downregulation of TNF-alpha and IL-1beta by CGS21680 was less affected by PPARgamma knockdown. | 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine | interleukin 1 alpha | Mus musculus |