| 1 |
33656879 | Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5. | 2021 Mar 17 |
1 |
| 2 |
34662099 | Mechanism of the Clinically Relevant E305G Mutation in Human P450 CYP17A1. | 2021 Nov 2 |
1 |
| 3 |
31818479 | Prospective computational design and in vitro bio-analytical tests of new chemical entities as potential selective CYP17A1 lyase inhibitors. | 2020 Jan |
1 |
| 4 |
30431391 | Comparative study of the binding mode between cytochrome P450 17A1 and prostate cancer drugs in the absence of haem iron. | 2019 Oct |
4 |
| 5 |
29283561 | Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202. | 2018 Feb 6 |
1 |
| 6 |
27566228 | Structural insights into the function of steroidogenic cytochrome P450 17A1. | 2017 Feb 5 |
1 |
| 7 |
28387522 | Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions. | 2017 May 22 |
3 |
| 8 |
25988615 | A new pregnenolone analogues as privileged scaffolds in inhibition of CYP17 hydroxylase enzyme. Synthesis and in silico molecular docking study. | 2015 Aug |
1 |
| 9 |
26051784 | New biaryl-chalcone derivatives of pregnenolone via Suzuki-Miyaura cross-coupling reaction. Synthesis, CYP17 hydroxylase inhibition activity, QSAR, and molecular docking study. | 2015 Sep |
1 |
| 10 |
26682016 | Comparisons of Prostate Cancer Inhibitors Abiraterone and TOK-001 Binding with CYP17A1 through Molecular Dynamics. | 2015 |
1 |
| 11 |
25251696 | New CYP17 hydroxylase inhibitors: synthesis, biological evaluation, QSAR, and molecular docking study of new pregnenolone analogs. | 2014 Dec |
1 |
| 12 |
23576395 | Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry. | 2013 May 10 |
1 |
| 13 |
22266943 | Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001. | 2012 Jan 22 |
1 |
| 14 |
16473871 | Generation of 3D templates of active sites of proteins with rigid prosthetic groups. | 2006 May 15 |
1 |
| 15 |
16176874 | Novel mutation of the CYP17 gene in two unrelated patients with combined 17alpha-hydroxylase/17,20-lyase deficiency: demonstration of absent enzyme activity by expressing the mutant CYP17 gene and by three-dimensional modeling. | 2005 Nov |
1 |
| 16 |
12773039 | Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy. | 2003 Jun 5 |
2 |