| 1 |
31691616 | A rare enzymatic defect, true isolated 17,20-lyase deficiency leading to endocrine disorders and infertility: case report. | 2020 Apr |
1 |
| 2 |
32203088 | Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders. | 2020 May |
1 |
| 3 |
33780934 | Genotypic Sex and Severity of the Disease Determine the Time of Clinical Presentation in Steroid 17α-Hydroxylase/17,20-Lyase Deficiency. | 2020 |
1 |
| 4 |
31351131 | The crosstalk between aldosterone and calcium metabolism in primary aldosteronism: A possible calcium metabolism-associated aberrant "neoplastic" steroidogenesis in adrenals. | 2019 Oct |
2 |
| 5 |
31356544 | CYP17A1 Polymorphisms Are Linked to the Risk of Coronary Heart Disease in a Case-Control Study. | 2019 Aug |
2 |
| 6 |
31397841 | Adrenocortical Carcinoma Xenograft in Zebrafish Embryos as a Model To Study the In Vivo Cytotoxicity of Abiraterone Acetate. | 2019 Nov 1 |
1 |
| 7 |
29065432 | PreImplantation Factor (PIF*) Regulates Stress-Induced Adrenal Steroidogenesis and Anti-Inflammatory Cytokines: Potential Application for Bioartificial Adrenal Transplant. | 2018 Feb |
2 |
| 8 |
29229304 | Functional characterization of the G162R and D216H genetic variants of human CYP17A1. | 2018 Apr |
2 |
| 9 |
27702589 | Electrochemistry of cytochrome P450 17α-hydroxylase/17,20-lyase (P450c17). | 2017 Feb 5 |
1 |
| 10 |
28000554 | A Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17. | 2017 |
1 |
| 11 |
28487303 | Female phenotype with male karyotype: a clinical enigma. | 2017 May 9 |
1 |
| 12 |
28893623 | CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2. | 2017 Nov |
1 |
| 13 |
26514241 | Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1). | 2016 |
2 |
| 14 |
26597777 | Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17. | 2016 Feb 15 |
1 |
| 15 |
27789139 | Design, synthesis, and evaluation of (2S,4R)-Ketoconazole sulfonamide analogs as potential treatments for Metabolic Syndrome. | 2016 Dec 1 |
1 |
| 16 |
25224484 | The post-translational regulation of 17,20 lyase activity. | 2015 Jun 15 |
1 |
| 17 |
26161337 | A case of 17 alpha-hydroxylase deficiency. | 2015 Jun |
1 |
| 18 |
26701948 | An easily missed diagnosis: 17-alpha-hydroxylase/17,20-lyase deficiency. | 2015 May-Jun |
2 |
| 19 |
23254310 | The effect of mitotane on viability, steroidogenesis and gene expression in NCI‑H295R adrenocortical cells. | 2013 Mar |
1 |
| 20 |
22170708 | Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer. | 2012 Feb |
1 |
| 21 |
21094146 | Steroid synthesis by primary human keratinocytes; implications for skin disease. | 2011 Jan 7 |
1 |
| 22 |
21848792 | Increased expression of CYP17 and CYP11B1 in subclinical Cushing's syndrome due to adrenal adenomas. | 2011 Oct |
1 |
| 23 |
20160131 | Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a. | 2010 Apr |
1 |
| 24 |
19270420 | Cushing's syndrome by left adrenocortical adenoma synchronously associated with primary aldosteronism by right adrenocortical adenoma: report of a case. | 2009 |
1 |
| 25 |
19564722 | Increased ratio of mRNA expression of the genes CYP17 and CYP11B1 indicates autonomous cortisol production in adrenocortical tumors. | 2009 Nov |
3 |
| 26 |
18422032 | Novel mutation in cytochrome P450c17 causes complete combined 17alpha-hydroxylase/17,20-lyase deficiency. | 2008 Feb |
2 |
| 27 |
17400813 | Expression of molecular equivalent of hypothalamic-pituitary-adrenal axis in adult retinal pigment epithelium. | 2007 Apr |
1 |
| 28 |
17408424 | Benign cortisol-secreting adrenocortical adenomas produce small amounts of androgens. | 2007 Jun |
1 |
| 29 |
15128284 | Modulation of steroidogenic enzymes by orphan nuclear transcriptional regulation may control diverse production of cortisol and androgens in the human adrenal. | 2004 May |
1 |
| 30 |
15248825 | Postoperative differentiation between unilateral adrenal adenoma and bilateral adrenal hyperplasia in primary aldosteronism by mRNA expression of the gene CYP11B2. | 2004 Jul |
1 |
| 31 |
12444089 | Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. | 2003 Jan 31 |
1 |
| 32 |
12608705 | New aspects on primary aldosteronism. | 2003 Feb |
1 |
| 33 |
12924498 | A report of 7 cases of adrenal tumors secreting both cortisol and aldosterone. | 2003 Aug |
2 |
| 34 |
12044959 | Mechanism of action of anti-aging DHEA-S and the replacement of DHEA-S. | 2002 Apr 30 |
1 |
| 35 |
11463853 | NF-1C, Sp1, and Sp3 are essential for transcription of the human gene for P450c17 (steroid 17alpha-hydroxylase/17,20 lyase) in human adrenal NCI-H295A cells. | 2001 Aug |
1 |
| 36 |
11572038 | In vitro release of aldosterone and cortisol in human adrenal adenomas correlates to mRNA expression of steroidogenic enzymes for genes CYP11B2 and CYP17. | 2001 Jul |
1 |
| 37 |
10824109 | Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone. | 2000 Jun |
1 |
| 38 |
11196462 | Expression and regulation of BCL-2 family genes in human adrenocortical adenomas in comparison with adrenal hyperplasia of Cushing's disease. | 2000 Nov |
1 |
| 39 |
9931027 | Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species. | 1999 Feb 2 |
1 |
| 40 |
8732456 | Incidentally discovered adrenocortical adenomas are not fully nonfunctioning: immunohistochemical and dispersed adrenocortical cell study. | 1996 Feb |
1 |
| 41 |
1835446 | Markedly increased expression of cytochrome P-450 17 alpha-hydroxylase (P-450c17) mRNA in adrenocortical adenomas from patients with Cushing's syndrome. | 1991 Sep |
1 |
| 42 |
3077248 | Molecular genetics of congenital adrenal hyperplasia. | 1988 Nov |
1 |