Title : CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2.

Pub. Date : 2017 Nov

PMID : 28893623






1 Functional Relationships(s)
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1 A loss of CYP21A2 activity in combination with reduction of CYP17A1 activities by abiraterone could result in lower cortisol levels and may require monitoring for any potential adverse effects. Hydrocortisone cytochrome P450 family 17 subfamily A member 1 Homo sapiens