Fatty Acids

toll like receptor 4 ; Homo sapiens







53 Article(s)
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1 35228371 [Homeostatic and Pathophysiological Regulation of Toll-like Receptor 4 Signaling by GM3 Ganglioside Molecular Species]. 2022 3
2 35490239 Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome. 2022 May 1 2
3 34363204 Sphingolipid metabolism during Toll-like receptor 4 (TLR4)-mediated macrophage activation. 2021 Dec 2
4 31870728 A global perspective on the crosstalk between saturated fatty acids and Toll-like receptor 4 in the etiology of inflammation and insulin resistance. 2020 Jan 3
5 32403975 Role of TLR4 in the induction of inflammatory changes in adipocytes and macrophages. 2020 Dec 1
6 29857009 Saturated fatty acids, obesity, and the nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in asthmatic patients. 2019 Jan 2
7 31123414 Downregulation of MALAT1 alleviates saturated fatty acid-induced myocardial inflammatory injury via the miR-26a/HMGB1/TLR4/NF-κB axis. 2019 2
8 29494148 Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists. 2018 Apr 12 1
9 29601492 Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids. 2018 Mar 30 2
10 29636416 TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c+ adipose tissue macrophage production in obese mice. 2018 Jun 8 1
11 29667734 Celastrol reverses palmitic acid (PA)-caused TLR4-MD2 activation-dependent insulin resistance via disrupting MD2-related cellular binding to PA. 2018 Oct 1
12 28041958 SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. 2017 Feb 7 2
13 28088520 Palmitic acid increases invasiveness of pancreatic cancer cells AsPC-1 through TLR4/ROS/NF-κB/MMP-9 signaling pathway. 2017 Feb 26 1
14 28137586 High-density lipoprotein and apolipoprotein A-I inhibit palmitate-induced translocation of toll-like receptor 4 into lipid rafts and inflammatory cytokines in 3T3-L1 adipocytes. 2017 Mar 4 2
15 28344752 Involvement of Cbl-b-mediated macrophage inactivation in insulin resistance. 2017 Mar 15 2
16 28463985 Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β. 2017 3
17 28571793 Saturated fatty acids recognition by the CD14-TLR4-MD2 complex may engage in the presurgical anxiety-induced persistent postsurgical pain. 2017 Jun 1
18 27085899 Mechanisms for the activation of Toll-like receptor 2/4 by saturated fatty acids and inhibition by docosahexaenoic acid. 2016 Aug 15 3
19 27599658 GSK-3β-mediated fatty acid synthesis enhances epithelial to mesenchymal transition of TLR4-activated colorectal cancer cells through regulation of TAp63. 2016 Nov 3
20 25358453 Elaidate, an 18-carbon trans-monoenoic fatty acid, but not physiological fatty acids increases intracellular Zn(2+) in human macrophages. 2015 Apr 1
21 25811237 TLR4 at the Crossroads of Nutrients, Gut Microbiota, and Metabolic Inflammation. 2015 Jun 2
22 25984739 MiRNA-194 Regulates Palmitic Acid-Induced Toll-Like Receptor 4 Inflammatory Responses in THP-1 Cells. 2015 May 13 1
23 26045709 Saturated Fatty Acid inhibits viral replication in chronic hepatitis B virus infection with nonalcoholic Fatty liver disease by toll-like receptor 4-mediated innate immune response. 2015 May 2
24 26084695 Selective overexpression of Toll-like receptor-4 in skeletal muscle impairs metabolic adaptation to high-fat feeding. 2015 Aug 1 3
25 26113297 Hepatic TLR4 signaling in obese NAFLD. 2015 Aug 15 1
26 26202921 Saturated fatty acids enhance TLR4 immune pathways in human trophoblasts. 2015 Sep 3
27 26245186 Fatty acids from fat cell lipolysis do not activate an inflammatory response but are stored as triacylglycerols in adipose tissue macrophages. 2015 Nov 1
28 24221358 Saturated fatty acids up-regulate COX-2 expression in prostate epithelial cells via toll-like receptor 4/NF-κB signaling. 2014 Apr 1
29 23275648 Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4. 2013 Mar 3
30 23909843 The dual role of free fatty acid signaling in inflammation and therapeutics. 2013 Sep 1
31 23958744 Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer. 2013 Nov 15 1
32 22700961 NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response. 2012 Jul 27 1
33 22766885 Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways. 2012 Sep 6
34 23050932 TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipid-induced inflammation and insulin resistance in muscle cells. 2012 Nov 30 2
35 23259689 Fatty acids do not pay the toll: effect of SFA and PUFA on human adipose tissue and mature adipocytes inflammation. 2012 Dec 21 2
36 21336404 Synthesis of serine-based glycolipids as potential TLR4 activators. 2011 Apr 7 1
37 20110572 Nutrient modification of the innate immune response: a novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation. 2010 Apr 2
38 20179247 Toll-like receptor 4 modulates skeletal muscle substrate metabolism. 2010 May 4
39 20360405 Adipose tissue macrophages: their role in adipose tissue remodeling. 2010 Jul 1
40 20434953 Innate immunity and adipose tissue biology. 2010 Jun 1
41 19277946 The c-Jun N-terminal kinase mediates the induction of oxidative stress and insulin resistance by palmitate and toll-like receptor 2 and 4 ligands in 3T3-L1 adipocytes. 2009 Jul 2
42 19375453 Dietary factors lead to innate immune activation in asthma. 2009 Jul 4
43 19440711 The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease? 2009 Sep 1
44 19563447 Fatty acids as metabolic mediators in innate immunity. 2009 Oct 1
45 19625959 Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome. 2009 Oct 1
46 19648648 Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. 2009 Oct 2 5
47 19661481 Saturated fatty acids do not directly stimulate Toll-like receptor signaling. 2009 Nov 2
48 17911231 Integrating the immune system with the regulation of growth and efficiency. 2008 Apr 1
49 17141623 Fat uses a TOLL-road to connect inflammation and diabetes. 2006 Dec 1
50 14966134 Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1. 2004 Apr 23 4