Pub. Date : 2016 Aug 15
PMID : 27085899
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Saturated fatty acids can activate Toll-like receptor 2 (TLR2) and TLR4 but polyunsaturated fatty acids, particularly docosahexaenoic acid (DHA) inhibit the activation. | Fatty Acids | toll like receptor 4 | Homo sapiens |
| 2 | Lipopolysaccharides (LPS) and lipopetides, ligands for TLR4 and TLR2, respectively, are acylated by saturated fatty acids. | Fatty Acids | toll like receptor 4 | Homo sapiens |
| 3 | Saturated fatty acids also induce the dimerization and translocation of TLR4 and TLR2 into lipid rafts in plasma membrane and this process is inhibited by DHA. | Fatty Acids | toll like receptor 4 | Homo sapiens |