| 1 |
35194137 | Hemojuvelin deficiency promotes liver mitochondrial dysfunction and predisposes mice to hepatocellular carcinoma. | 2022 Feb 22 |
4 |
| 2 |
33180328 | Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model. | 2021 Feb 1 |
1 |
| 3 |
33942901 | SLN124, a GalNac-siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron-overload in a mouse model of β-thalassaemia. | 2021 Jul |
1 |
| 4 |
34558857 | Tissue-Specific Regulation of Ferroportin in Wild-Type and Hjv-/- Mice Following Dietary Iron Manipulations. | 2021 Dec |
1 |
| 5 |
29636509 | Matriptase-2 deficiency protects from obesity by modulating iron homeostasis. | 2018 Apr 10 |
1 |
| 6 |
30213871 | Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling. | 2018 Oct 25 |
4 |
| 7 |
27864295 | Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice. | 2017 Jan 26 |
1 |
| 8 |
28115312 | Females Are Protected From Iron-Overload Cardiomyopathy Independent of Iron Metabolism: Key Role of Oxidative Stress. | 2017 Jan 23 |
1 |
| 9 |
29021231 | Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge. | 2017 Nov 23 |
4 |
| 10 |
26077449 | Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload. | 2016 Feb |
1 |
| 11 |
26845567 | Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats. | 2016 |
1 |
| 12 |
27046124 | Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis. | 2016 Apr |
1 |
| 13 |
27072365 | Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver. | 2016 Jun 3 |
4 |
| 14 |
28203489 | Effects of Anti-repulsive Guidance Molecule C (RGMc/Hemojuvelin) Antibody on Hepcidin and Iron in Mouse Liver and Tumor Xenografts. | 2016 Nov |
2 |
| 15 |
25501544 | A high-fat diet modulates iron metabolism but does not promote liver fibrosis in hemochromatotic Hjv⁻/⁻ mice. | 2015 Feb 15 |
5 |
| 16 |
25608116 | HJV and HFE Play Distinct Roles in Regulating Hepcidin. | 2015 May 20 |
3 |
| 17 |
25609138 | Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin. | 2015 May |
4 |
| 18 |
26027705 | Deficits of learning and memory in Hemojuvelin knockout mice. | 2015 Oct |
2 |
| 19 |
24409331 | Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels. | 2014 |
4 |
| 20 |
24808863 | Hepcidin antagonists for potential treatments of disorders with hepcidin excess. | 2014 |
1 |
| 21 |
24812553 | Deletion of hemojuvelin, an iron-regulatory protein, in mice results in abnormal angiogenesis and vasculogenesis in retina along with reactive gliosis. | 2014 May 8 |
3 |
| 22 |
25220979 | mRNA regulation of cardiac iron transporters and ferritin subunits in a mouse model of iron overload. | 2014 Dec |
1 |
| 23 |
22875629 | A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum. | 2013 Feb |
5 |
| 24 |
21943374 | Iron-mediated retinal degeneration in haemojuvelin-knockout mice. | 2012 Jan 15 |
5 |
| 25 |
21993681 | Hemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression in mice. | 2012 Feb |
2 |
| 26 |
22244935 | Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6. | 2012 Mar 15 |
1 |
| 27 |
22629388 | Effect of iron overload and iron deficiency on liver hemojuvelin protein. | 2012 |
2 |
| 28 |
20940420 | Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6. | 2011 Jan 13 |
2 |
| 29 |
21187450 | Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages. | 2011 Feb 1 |
1 |
| 30 |
21480335 | Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. | 2011 Apr |
6 |
| 31 |
21493799 | Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis. | 2011 Jun 9 |
1 |
| 32 |
21748766 | Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin. | 2011 Nov |
6 |
| 33 |
21936923 | Liver and muscle hemojuvelin are differently glycosylated. | 2011 Sep 21 |
2 |
| 34 |
19249912 | Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin. | 2010 |
1 |
| 35 |
20065295 | Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. | 2010 Apr 15 |
3 |
| 36 |
20200349 | Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis. | 2010 May 6 |
2 |
| 37 |
20363739 | The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo. | 2010 May 28 |
1 |
| 38 |
20542038 | Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment. | 2010 Aug |
8 |
| 39 |
20858542 | Conserved proximal promoter elements control repulsive guidance molecule c/hemojuvelin (Hfe2) gene transcription in skeletal muscle. | 2010 Dec |
3 |
| 40 |
18997172 | Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness. | 2009 Jan 15 |
1 |
| 41 |
19191760 | Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection. | 2009 May 1 |
4 |
| 42 |
19234060 | Deferasirox reduces iron overload in a murine model of juvenile hemochromatosis. | 2009 May |
4 |
| 43 |
19252486 | BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. | 2009 Apr |
2 |
| 44 |
19751239 | Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6. | 2009 Nov |
3 |
| 45 |
17938254 | Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. | 2008 Jan 15 |
3 |
| 46 |
18521557 | Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression. | 2008 Jul |
1 |
| 47 |
17255318 | Repression of repulsive guidance molecule C during inflammation is independent of Hfe and involves tumor necrosis factor-alpha. | 2007 Feb |
1 |
| 48 |
17264300 | Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. | 2007 May 15 |
2 |
| 49 |
16801541 | Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6. | 2006 Jul 5 |
1 |
| 50 |
16868025 | Complex biosynthesis of the muscle-enriched iron regulator RGMc. | 2006 Aug 15 |
2 |