Title : A high-fat diet modulates iron metabolism but does not promote liver fibrosis in hemochromatotic Hjv⁻/⁻ mice.

Pub. Date : 2015 Feb 15

PMID : 25501544






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Hemojuvelin (Hjv) is a membrane protein that controls body iron metabolism by enhancing signaling to hepcidin. Iron hemojuvelin BMP co-receptor Mus musculus
2 Hemojuvelin (Hjv) is a membrane protein that controls body iron metabolism by enhancing signaling to hepcidin. Iron hemojuvelin BMP co-receptor Mus musculus
3 Hjv mutations cause juvenile hemochromatosis, a disease of systemic iron overload. Iron hemojuvelin BMP co-receptor Mus musculus
4 The aim of this study was to investigate the pathological implications of parenchymal iron overload due to Hjv ablation in the fatty liver. Iron hemojuvelin BMP co-receptor Mus musculus
5 As expected, all Hjv(-/-) mice manifested higher serum and hepatic iron and diminished hepcidin levels compared with WT controls. Iron hemojuvelin BMP co-receptor Mus musculus