Title : Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels.

Pub. Date : 2014

PMID : 24409331






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Hemojuvelin (Hjv) is a bone morphogenetic protein (BMP) co-receptor involved in the control of systemic iron homeostasis. Iron hemojuvelin BMP co-receptor Mus musculus
2 Hemojuvelin (Hjv) is a bone morphogenetic protein (BMP) co-receptor involved in the control of systemic iron homeostasis. Iron hemojuvelin BMP co-receptor Mus musculus
3 Hjv-/- mice developed systemic iron overload under all regimens. Iron hemojuvelin BMP co-receptor Mus musculus
4 These findings suggest that Hjv is not required for sensing of body iron levels and merely functions as an enhancer for iron signaling to hepcidin. Iron hemojuvelin BMP co-receptor Mus musculus