2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

transforming growth factor, beta 1 ; Rattus norvegicus







49 Article(s)
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1 31729763 TGF-β1 activates RSC96 Schwann cells migration and invasion through MMP-2 and MMP-9 activities. 2020 May 1
2 27025157 Bisphenol A, an environmental estrogen-like toxic chemical, induces cardiac fibrosis by activating the ERK1/2 pathway. 2016 May 27 2
3 25231827 Second messengers mediating the proliferation and collagen synthesis of tenocytes induced by low-level laser irradiation. 2015 Jan 1
4 25560488 MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells. 2015 May 1
5 25592322 Role of eukaryotic translation initiation factor 3a in bleomycin-induced pulmonary fibrosis. 2015 Feb 15 1
6 26075533 TGF-β1 antagonizes TNF-α induced up-regulation of matrix metalloproteinase 3 in nucleus pulposus cells: role of the ERK1/2 pathway. 2015 Nov 1
7 26136938 Quercetin promotes the osteogenic differentiation of rat mesenchymal stem cells via mitogen-activated protein kinase signaling. 2015 Jun 1
8 26165845 Transforming growth factor-β1 induces type II collagen and aggrecan expression via activation of extracellular signal-regulated kinase 1/2 and Smad2/3 signaling pathways. 2015 Oct 1
9 24001173 Hypoxia activates muscle-restricted coiled-coil protein (MURC) expression via transforming growth factor-β in cardiac myocytes. 2014 Mar 1
10 25245272 Interaction of ERK1/2 and Smad2/3 signaling pathways in TGF-β1-induced TIMP-3 expression in rat chondrocytes. 2014 Dec 15 1
11 25406076 Role of moesin in renal fibrosis. 2014 1
12 22285838 High glucose enhances TGF-β1 expression in rat bone marrow stem cells via ERK1/2-mediated inhibition of STAT3 signaling. 2012 Apr 9 1
13 22521802 Transforming growth factor-β increases vascular smooth muscle cell proliferation through the Smad3 and extracellular signal-regulated kinase mitogen-activated protein kinases pathways. 2012 Aug 1
14 22659623 The mineralocorticoid receptor-p38MAPK-NFκB or ERK-Sp1 signal pathways mediate aldosterone-stimulated inflammatory and profibrotic responses in rat vascular smooth muscle cells. 2012 Jul 1
15 22764581 Fluorofenidone inhibits transforming growth factor-beta1-induced cardiac myofibroblast differentiation. 2012 May 2
16 21367774 Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts. 2011 Jul 1 1
17 21925118 Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells. 2011 Oct 1
18 20432467 Src is a major signaling component for CTGF induction by TGF-beta1 in osteoblasts. 2010 Sep 1
19 20466671 Triptolide inhibits extracellular matrix protein synthesis by suppressing the Smad2 but not the MAPK pathway in TGF-beta1-stimulated NRK-49F cells. 2010 Oct 2
20 20590658 MEK/ERK and p38 MAPK regulate chondrogenesis of rat bone marrow mesenchymal stem cells through delicate interaction with TGF-beta1/Smads pathway. 2010 Aug 1
21 19194552 Aldosterone-induced TGF-beta1 expression is regulated by mitogen-activated protein kinases and activator protein-1 in mesangial cells. 2009 Jan 1
22 19960006 Adenosine 5'-triphosphate stimulates the increase of TGF-beta1 in rat mesangial cells under high-glucose conditions via reactive oxygen species and ERK1/2. 2009 Dec 1
23 18234639 An experimental study of extracellular signal-regulated kinase and its interventional treatments in hepatic fibrosis. 2008 Feb 1
24 18314002 Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts. 2008 May 1
25 19061498 Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF beta-1 in cultured rat nucleus pulposus cells. 2008 1
26 17650227 Effects of extracellular signal-regulated kinase on rat cultured hepatic stellate cells stimulated by acetaldehyde. 2007 Aug 1
27 16371439 Autocrine loop between TGF-beta1 and IL-1beta through Smad3- and ERK-dependent pathways in rat pancreatic stellate cells. 2006 Apr 1
28 16598747 Existence of autocrine loop between interleukin-6 and transforming growth factor-beta1 in activated rat pancreatic stellate cells. 2006 Sep 1 1
29 15622520 Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent. 2005 Jul 2
30 15703462 Differential effects of transforming growth factor-beta on the synthesis of connective tissue growth factor and vascular endothelial growth factor by peritoneal mesothelial cell. 2005 1
31 16029631 [Connective tissue growth factor promotes the proliferation of myofibroblast through Erk-1/2 signaling pathway]. 2005 May 25 1
32 12952860 ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells. 2004 Jan 1
33 12865256 The interrelationship between TGF-beta1 and nitric oxide is altered in salt-sensitive hypertension. 2003 Nov 1
34 12875981 Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction. 2003 Aug 1
35 14575868 Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2. 2003 Dec 1
36 12029621 Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line. 2002 Jun 1
37 12206991 Dietary salt intake activates MAP kinases in the rat kidney. 2002 Oct 1
38 11401854 Smad4 mediates activation of mitogen-activated protein kinases by TGF-beta in pancreatic acinar cells. 2001 Jul 3
39 11483646 Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways. 2001 Aug 3
40 11679965 Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts. 2001 Nov 2
41 11707697 Cardioprotective effects of transforming growth factor-beta1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK. 2001 Dec 1
42 11716483 Involvement of MAP kinase cascades in Smad7 transcriptional regulation. 2001 Nov 30 1
43 10880840 Association of decreased phosphorylation of ERK-2 with costimulation of rat T cell activation by MEK-1 inhibitors and TGF-beta1. 2000 Jun 1 1
44 10966845 Dexamethasone inhibition of TGF beta-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes. 2000 Sep 1
45 10997694 Role of mitogen-activated protein kinases as downstream effectors of transforming growth factor-beta in mesangial cells. 2000 Sep 1
46 10208426 Cross-talk between the Smad1 and Ras/MEK signaling pathways for TGFbeta. 1999 Mar 18 2
47 10406835 Contribution of extracellular signal-regulated kinase to angiotensin II-induced transforming growth factor-beta1 expression in vascular smooth muscle cells. 1999 Jul 1
48 10580747 Transforming growth factor-beta stimulates articular chondrocyte cell growth through p44/42 MAP kinase (ERK) activation. 1999 Aug 2
49 10935498 Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. 1999 Dec 1