Title : Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts.

Pub. Date : 2008 May

PMID : 18314002






1 Functional Relationships(s)
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1 To confirm the vital role of Erk, we used the Erk inhibitor (PD98059) to block its activation, demonstrating that it prevented TGF-beta1 activation of the CTGF promoter and up-regulation of CTGF expression in osteoblasts. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one transforming growth factor, beta 1 Rattus norvegicus