Diglycerides

proline rich transmembrane protein 2 ; Homo sapiens







128 Article(s)
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51 11728178 Conformationally constrained analogues of diacylglycerol. 18. The incorporation of a hydroxamate moiety into diacylglycerol-lactones reduces lipophilicity and helps discriminate between sn-1 and sn-2 binding modes to protein kinase C (PK-C). Implications for isozyme specificity. 2001 Dec 6 6
52 10715158 Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C? 2000 Mar 9 6
53 10762046 Diacylglycerols with lipophilically equivalent branched acyl chains display high affinity for protein kinase C (PK-C). A direct measure of the effect of constraining the glycerol backbone in DAG lactones. 2000 Apr 3 2
54 10837365 Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. 2000 Jun 2
55 10966739 Conformationally constrained analogues of diacylglycerol (DAG). 17. Contrast between sn-1 and sn-2 DAG lactones in binding to protein kinase C. 2000 Aug 24 7
56 11465069 Protein kinase C as a drug target: implications for drug or diet prevention and treatment of cancer. 2000 Sep 2
57 10209246 Muscarinic receptor- and phorbol ester-stimulated phosphorylation of protein kinase C substrates in adult and neonatal cortical slices. 1999 Apr 12 1
58 10380910 Protein kinase C and a calcium-independent phospholipase are required for IgG-mediated phagocytosis by Mono-Mac-6 cells. 1999 Jun 2
59 10588370 Can protein kinase C inhibition and vitamin E prevent the development of diabetic vascular complications? 1999 Sep 4
60 10629766 Free PKC catalytic subunits (PKM) phosphorylate tau via a pathway distinct from that utilized by intact PKC. 1999 Dec 11 5
61 9446641 Protein kinase C mediates the mitogenic action of thrombopoietin in c-Mpl-expressing UT-7 cells. 1998 Feb 1 1
62 9510544 Upregulation of a Hydra vulgaris cPKC gene is tightly coupled to the differentiation of head structures. 1998 Feb 1
63 9617479 Protein kinase C and the cytoskeleton. 1998 Apr 1
64 9670214 Protein kinase C: a physiological mediator of enhanced transmitter output. 1998 Aug 2
65 9814702 Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals. 1998 Oct 30 3
66 9099897 Prolactin regulation of mitochondrial aspartate aminotransferase and protein kinase C in human prostate cancer cells. 1997 Mar 14 1
67 9237245 The biochemistry of the acrosome reaction. 1997 Mar 2
68 9269538 Protein kinase C and transmitter release. 1997 Aug 2
69 8568819 Conformationally constrained analogues of diacylglycerol. 11. Ultrapotent protein kinase C ligands based on a chiral 5-disubstituted tetrahydro-2-furanone template. 1996 Jan 5 6
70 8613911 Protein kinase C mediates spontaneous tone in the cat lower esophageal sphincter. 1996 Apr 2
71 8700857 Chemical specificity and physical properties of the lipid bilayer in the regulation of protein kinase C by anionic phospholipids: evidence for the lack of a specific binding site for phosphatidylserine. 1996 Mar 5 1
72 8712775 Myocardial preconditioning promises to be a novel approach to the treatment of ischemic heart disease. 1996 1
73 8805373 Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha. 1996 Sep 1 1
74 8820410 Reorientational properties of fluorescent analogues of the protein kinase C cofactors diacylglycerol and phorbol ester. 1996 Feb 8 3
75 8876672 ras downregulation of protein kinase C mRNA in C3H 10T1/2 fibroblasts. 1996 Sep 1
76 8960550 Conformationally constrained analogues of diacylglycerol. 13. Protein kinase C ligands based on templates derived from 2,3-dideoxy-L-erythro(threo)-hexono-1,4-lactone and 2-deoxyapiolactone. 1996 Dec 6 1
77 9015863 Phosphoinositide-dependent in vitro phosphorylation of profilin by protein kinase C. Phospholipid specificity and localization of the phosphorylation site. 1996 2
78 12232621 The Accumulation of Diacylglycerol and Activation of Protein Kinase C Induced by High K(+) Exposure in the Frog Skeletal Muscle. 1996 3
79 7485441 Protein kinase C in cyclic stretch-induced nerve growth factor production by urinary tract smooth muscle cells. 1995 Oct 1
80 7493994 Phosphorylation of the platelet p47 phosphoprotein is mediated by the lipid products of phosphoinositide 3-kinase. 1995 Dec 8 1
81 7783402 High glucose concentrations and protein kinase C isoforms in vascular smooth muscle cells. 1995 Apr 2
82 8519996 Effects of diacylglycerols on conformation of phosphatidylcholine headgroups in phosphatidylcholine/phosphatidylserine bilayers. 1995 Sep 9
83 8532710 The tumor promoter receptor protein kinase C: a novel target for chemoprevention and therapy of human colon cancer. 1995 1
84 7712599 Regulation of protein kinase C and role in cancer biology. 1994 Dec 2
85 7803515 Protein kinase C expression and translocation in dispersed chief cells from guinea-pig stomach. 1994 Dec 30 1
86 8074672 Purification and characterization of protein kinase C from a higher plant, Brassica campestris L. 1994 Aug 30 1
87 8130278 Effect of fatty acids and their acyl-CoA esters on protein kinase C activity in fibroblasts: possible implications in fatty acid oxidation defects. 1994 Mar 10 2
88 28305948 Protein kinase C in hydrozoans: involvement in metamorphosis of Hydractinia and in pattern formation of Hydra. 1994 Aug 2
89 8344386 PKC activity and PKC-alpha mRNA content are reduced in serum-derived human neuroblastoma cells without concomitant induction of differentiation. 1993 Aug 1
90 8374745 Involvement of protein kinase C in the proliferation of cultured Schwann cells. 1993 Jul 16 1
91 8390801 Shape changes and chemokinesis of Walker carcinosarcoma cells: effects of protein kinase inhibitors (HA-1004, polymyxin B, sangivamycin and tamoxifen) and an inhibitor of diacylglycerol kinase (R 59022). 1993 Mar-Apr 3
92 8405692 Diacylglycerol content of Chaetopterus oocytes during maturation and fertilization. 1993 Oct 1
93 8430818 Tumor necrosis factor-alpha activates pulmonary artery endothelial protein kinase C. 1993 Jan 3
94 8432785 Protein kinase-C stimulatory activity in human amnion cytosol. 1993 Feb 1
95 8440177 Regulation of parathyroid hormone release by protein kinase-C is dependent on extracellular calcium in bovine parathyroid cells. 1993 Mar 1
96 8480534 Therapeutic potential of protein kinase C inhibitors. 1993 Jan 2
97 1303731 Localization of subspecies of protein kinase C in the mammalian central nervous system. 1992 Dec 2
98 1323204 Regulation of phospholipid hydrolysis and second messenger formation by protein kinase C. 1992 4
99 1335820 Evidence for hippocampal calcium channel regulation by PKC based on comparison of diacylglycerols and phorbol esters. 1992 Nov 27 2
100 1370476 Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1. 1992 Jan 25 1