Title : Free PKC catalytic subunits (PKM) phosphorylate tau via a pathway distinct from that utilized by intact PKC.

Pub. Date : 1999 Dec 11

PMID : 10629766






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Protein kinase C (PKC) is reversibly activated at the plasma membrane by the generation of diacylglycerol (DAG) coupled with the release of Ca2+ from intracellular stores. Diglycerides proline rich transmembrane protein 2 Homo sapiens
2 Protein kinase C (PKC) is reversibly activated at the plasma membrane by the generation of diacylglycerol (DAG) coupled with the release of Ca2+ from intracellular stores. Diglycerides proline rich transmembrane protein 2 Homo sapiens
3 Protein kinase C (PKC) is reversibly activated at the plasma membrane by the generation of diacylglycerol (DAG) coupled with the release of Ca2+ from intracellular stores. Diglycerides proline rich transmembrane protein 2 Homo sapiens
4 Protein kinase C (PKC) is reversibly activated at the plasma membrane by the generation of diacylglycerol (DAG) coupled with the release of Ca2+ from intracellular stores. Diglycerides proline rich transmembrane protein 2 Homo sapiens
5 We examined the downstream consequences of PKC activation by the phorbol ester TPA and by ionophore A23187-mediated calcium influx (which experimentally correspond to DAG-mediated and calpain-mediated activation, respectively) on phosphorylation of the microtubule-associated protein tau. Diglycerides proline rich transmembrane protein 2 Homo sapiens