Title : Regulation of phospholipid hydrolysis and second messenger formation by protein kinase C.

Pub. Date : 1992

PMID : 1323204






4 Functional Relationships(s)
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Protein Name
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1 Treatment of platelets with inhibitors of PKC potentiates DAG mass formation in response to thrombin while prior activation of PKC with phorbol esters blocks DAG mass formation, consistent with PKC playing a negative feedback role, inhibiting inositol phospholipid breakdown. Diglycerides proline rich transmembrane protein 2 Homo sapiens
2 Treatment of platelets with inhibitors of PKC potentiates DAG mass formation in response to thrombin while prior activation of PKC with phorbol esters blocks DAG mass formation, consistent with PKC playing a negative feedback role, inhibiting inositol phospholipid breakdown. Diglycerides proline rich transmembrane protein 2 Homo sapiens
3 Treatment of platelets with inhibitors of PKC potentiates DAG mass formation in response to thrombin while prior activation of PKC with phorbol esters blocks DAG mass formation, consistent with PKC playing a negative feedback role, inhibiting inositol phospholipid breakdown. Diglycerides proline rich transmembrane protein 2 Homo sapiens
4 We have found that fibroblasts which overexpress the beta 1 isozyme of PKC display greatly enhanced DAG formation and phospholipase D activation in response to phorbol ester treatment. Diglycerides proline rich transmembrane protein 2 Homo sapiens