| 1 |
34653316 | Targeted SERPIN (TaSER): A dual-action antithrombotic agent that targets platelets for SERPIN delivery. | 2022 Feb |
2 |
| 2 |
35170548 | Potential applications of prognostic and immunological marker transmembrane serine proteinase 2 in prediction, prevention and personalized treatment of lung cancer. | 2022 Mar 3 |
1 |
| 3 |
35202850 | Combinatorial assembly, traceless generation and in situ evaluation of inhibitors for therapeutically relevant serine proteases. | 2022 Apr |
1 |
| 4 |
35239615 | The role of thrombin in haemostasis. | 2022 Apr 1 |
1 |
| 5 |
35352494 | Revised model of the tissue factor pathway of thrombin generation: Role of the feedback activation of FXI. | 2022 Jun |
2 |
| 6 |
35413630 | Ultrasensitive disposable apatasensor for reagentless electrocatalytic detection of thrombin: An O2-Dependent hemin-G4-aptamer assay on gold screen-printed electrodes. | 2022 Aug 1 |
1 |
| 7 |
35419655 | Simulations suggest double sodium binding induces unexpected conformational changes in thrombin. | 2022 Apr 13 |
1 |
| 8 |
32870433 | Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19. | 2021 Apr |
1 |
| 9 |
33411219 | Thrombin generation and activity in multiple sclerosis. | 2021 Mar |
2 |
| 10 |
33471524 | How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin. | 2021 Feb 11 |
1 |
| 11 |
33632104 | Serine Proteases and Chemokines in Neurotrauma: New Targets for Immune Modulating Therapeutics in Spinal Cord Injury. | 2021 |
1 |
| 12 |
33921354 | Role of Thrombin in Central Nervous System Injury and Disease. | 2021 Apr 12 |
1 |
| 13 |
33931701 | Serine protease dynamics revealed by NMR analysis of the thrombin-thrombomodulin complex. | 2021 Apr 30 |
1 |
| 14 |
34154000 | Thrombin: A Pivotal Player in Hemostasis and Beyond. | 2021 Oct |
1 |
| 15 |
34355714 | Preparation and application of quick hemostatic gauze based on biomimetic mineralized thrombin. | 2021 Sep 14 |
2 |
| 16 |
34792071 | Site-selective and inducible acylation of thrombin using aptamer-catalyst conjugates. | 2021 Dec 3 |
2 |
| 17 |
34809669 | TMPRSS4 promotes cancer stem-like properties in prostate cancer cells through upregulation of SOX2 by SLUG and TWIST1. | 2021 Nov 22 |
1 |
| 18 |
34869231 | Hindrance of the Proteolytic Activity of Neutrophil-Derived Serine Proteases by Serine Protease Inhibitors as a Management of Cardiovascular Diseases and Chronic Inflammation. | 2021 |
1 |
| 19 |
30302740 | Anti-tissue factor pathway inhibitor (TFPI) therapy: a novel approach to the treatment of haemophilia. | 2020 Jan |
1 |
| 20 |
32011145 | Protein-Induced Change in Ligand Protonation during Trypsin and Thrombin Binding: Hint on Differences in Selectivity Determinants of Both Proteins? | 2020 Mar 26 |
2 |
| 21 |
32234808 | Proteinase-Activated Receptor 4 Activation Triggers Cell Membrane Blebbing through RhoA and β-Arrestin. | 2020 Jun |
1 |
| 22 |
32792902 | Thrombin, a Mediator of Coagulation, Inflammation, and Neurotoxicity at the Neurovascular Interface: Implications for Alzheimer's Disease. | 2020 |
1 |
| 23 |
33260771 | In Silico Structural and Functional Characterization of HtrA Proteins of Leptospira spp.: Possible Implications in Pathogenesis. | 2020 Nov 28 |
1 |
| 24 |
30423352 | Individual Smad2 linker region phosphorylation sites determine the expression of proteoglycan and glycosaminoglycan synthesizing genes. | 2019 Jan |
2 |
| 25 |
30672691 | Thrombin Exosite Maturation and Ligand Binding at ABE II Help Stabilize PAR-Binding Competent Conformation at ABE I. | 2019 Feb 26 |
2 |
| 26 |
30889674 | Using Ca-doped carbon dots as catalyst to amplify signal to determine ultratrace thrombin by free-label aptamer-SERS method. | 2019 Jun |
3 |
| 27 |
31265898 | Aptamer-peptide conjugates as a new strategy to modulate human α-thrombin binding affinity. | 2019 Oct |
1 |
| 28 |
31501002 | TNF-α and IL-17A induce the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes. | 2019 Oct |
1 |
| 29 |
31524217 | A feasibility study of a leaky waveguide aptasensor for thrombin. | 2019 Oct 7 |
1 |
| 30 |
26729042 | Featured Article: Differential regulation of endothelial nitric oxide synthase phosphorylation by protease-activated receptors in adult human endothelial cells. | 2016 Mar |
1 |
| 31 |
27468101 | α1 -antitrypsin Pittsburgh and plasmin-mediated proteolysis. | 2016 Oct |
1 |
| 32 |
30609341 | [Direct Oral Anticoagulants (DOACs): Pharmacological Characteristics and Laboratory Assessment]. | 2016 Aug |
3 |
| 33 |
25664608 | Why Ser and not Thr brokers catalysis in the trypsin fold. | 2015 Feb 24 |
1 |
| 34 |
26355658 | Inhibitory Effects of Cytosolic Ca(2+) Concentration by Ginsenoside Ro Are Dependent on Phosphorylation of IP3RI and Dephosphorylation of ERK in Human Platelets. | 2015 |
1 |
| 35 |
26634958 | Dewetting of S1-Pocket via Water Channel upon Thrombin-Substrate Association Reaction. | 2015 Dec 31 |
1 |
| 36 |
24277696 | Thrombin-induced CCAAT/enhancer-binding protein β activation and IL-8/CXCL8 expression via MEKK1, ERK, and p90 ribosomal S6 kinase 1 in lung epithelial cells. | 2014 Jan 1 |
1 |
| 37 |
24378649 | PAR-1 activation rescues astrocytes through the PI3K/Akt signaling pathway from chemically induced apoptosis that is exacerbated by gene silencing of β-arrestin 1. | 2014 Feb |
3 |
| 38 |
25097470 | Antiphospholipid antibodies in localized scleroderma: the potential role of screening tests for the detection of antiphospholipid syndrome. | 2014 May |
1 |
| 39 |
23195954 | Serine protease activity of calnuc: regulation by Zn2+ and G proteins. | 2013 Jan 18 |
1 |
| 40 |
23254196 | Phytoestrogen genistein protects against endothelial barrier dysfunction in vascular endothelial cells through PKA-mediated suppression of RhoA signaling. | 2013 Feb |
1 |
| 41 |
23775088 | Crystal structure of prothrombin reveals conformational flexibility and mechanism of activation. | 2013 Aug 2 |
1 |
| 42 |
22234696 | Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets. | 2012 Apr 19 |
2 |
| 43 |
22344943 | Europium-labeled activity-based probe through click chemistry: absolute serine protease quantification using (153)Eu isotope dilution ICP/MS. | 2012 Apr 2 |
2 |
| 44 |
22828334 | The dynamic structure of thrombin in solution. | 2012 Jul 3 |
1 |
| 45 |
21109005 | Identification of three different types of serine proteases (one SP and two SPHs) in Chinese white shrimp. | 2011 Feb |
1 |
| 46 |
21592956 | mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]. | 2011 Jul 15 |
1 |
| 47 |
18768213 | Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro. | 2009 Mar |
1 |
| 48 |
19020052 | Histone H3 as a novel substrate for MAP kinase phosphatase-1. | 2009 Feb |
4 |
| 49 |
19494316 | Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway. | 2009 Jun 15 |
1 |
| 50 |
19530705 | Proton bridging in the interactions of thrombin with small inhibitors. | 2009 Aug 4 |
1 |