Title : Site-selective and inducible acylation of thrombin using aptamer-catalyst conjugates.

Pub. Date : 2021 Dec 3

PMID : 34792071






2 Functional Relationships(s)
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1 Modification occurred site-selectively on Lys (>>Ser) residues proximal to the respective aptamer-thrombin interface, was selective for thrombin in the presence of other proteins, and the activity of both DNA-catalysts could be controlled by an external trigger. Serine coagulation factor II, thrombin Homo sapiens
2 Modification occurred site-selectively on Lys (>>Ser) residues proximal to the respective aptamer-thrombin interface, was selective for thrombin in the presence of other proteins, and the activity of both DNA-catalysts could be controlled by an external trigger. Serine coagulation factor II, thrombin Homo sapiens