Pub. Date : 2014 Feb
PMID : 24378649
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, application of thrombin rescues beta-arrestin 1-lacking astrocytes from apoptosis by enhanced Akt (Ser 473) phosphorylation. | Serine | coagulation factor II, thrombin | Homo sapiens |
2 | Our most striking novel finding is that beta-arrestin 1 inhibits long-term thrombin-stimulated phosphorylation of Akt (Ser 473). | Serine | coagulation factor II, thrombin | Homo sapiens |
3 | In addition, we also found that thrombin-induced phosphorylation of Akt (Ser 473) is increased by transactivation of the EGF and PDGF receptors in beta-arrestin 1-silenced astrocytes. | Serine | coagulation factor II, thrombin | Homo sapiens |