SB 203580

tumor necrosis factor ; Homo sapiens







193 Article(s)
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51 20463356 Tumor necrosis factor stimulates matrix metalloproteinase 9 secretion from cultured human chorionic trophoblast cells through TNF receptor 1 signaling to IKBKB-NFKB and MAPK1/3 pathway. 2010 Sep 3
52 20484867 CV-159, a unique dihydropyridine derivative, prevents TNF-induced inflammatory responses in human umbilical vein endothelial cells. 2010 1
53 20589681 Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: does variable inhibition of interleukin-6 production limit effectiveness in vivo? 2010 Nov 1
54 20631885 Redox Factor-1 Inhibits Cyclooxygenase-2 Expression via Inhibiting of p38 MAPK in the A549 Cells. 2010 Jun 1
55 19201463 Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways. 2009 Apr 1
56 19320886 Migration of bone marrow-derived mesenchymal stem cells induced by tumor necrosis factor-alpha and its possible role in wound healing. 2009 Mar-Apr 2
57 19558546 Bovine glycomacropeptide induces cytokine production in human monocytes through the stimulation of the MAPK and the NF-kappaB signal transduction pathways. 2009 Aug 1
58 17683952 alpha-MSH inhibits TNF-alpha-induced matrix metalloproteinase-13 expression by modulating p38 kinase and nuclear factor kappaB signaling in human chondrosarcoma HTB-94 cells. 2008 Jan 1
59 17845838 Manganese-induced potentiation of in vitro proinflammatory cytokine production by activated microglial cells is associated with persistent activation of p38 MAPK. 2008 Feb 1
60 17940116 Progestin-inflammatory cytokine interactions affect matrix metalloproteinase-1 and -3 expression in term decidual cells: implications for treatment of chorioamnionitis-induced preterm delivery. 2008 Jan 1
61 18086260 TNF-alpha induction by Pseudomonas aeruginosa lipopolysaccharide or slime-glycolipoprotein in human monocytes is regulated at the level of Mitogen-activated Protein Kinase activity: a distinct role of Toll-like receptor 2 and 4. 2008 Feb 1
62 18086809 p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cells. 2008 Mar 1
63 18177344 Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells. 2008 Mar 1
64 18325031 Montelukast inhibits tumour necrosis factor-alpha-mediated interleukin-8 expression through inhibition of nuclear factor-kappaB p65-associated histone acetyltransferase activity. 2008 May 1
65 18357389 Activation of matrix metalloproteinase-9 by TNF-alpha in human urinary bladder cancer HT1376 cells: the role of MAP kinase signaling pathways. 2008 Apr 2
66 18440775 Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase. 2008 Jul 1
67 18442799 ERK and p38 MAP kinase are involved in downregulation of cell surface TNF receptor 1 induced by acetoxycycloheximide. 2008 Jun 1
68 18492658 The NF-kappaB, p38 MAPK and STAT1 pathways differentially regulate the dsRNA-mediated innate immune responses of epidermal keratinocytes. 2008 Jul 1
69 18492766 Wdnm1-like, a new adipokine with a role in MMP-2 activation. 2008 Jul 1
70 18613029 NF-kappaB, but not p38 MAP kinase, is required for TNF-alpha-induced expression of cell adhesion molecules in endothelial cells. 2008 Oct 1 4
71 18656701 Tumor necrosis factor-alpha up-regulates the expression of CCL2 and adhesion molecules of human proximal tubular epithelial cells through MAPK signaling pathways. 2008 1
72 18803934 The role of fatty acids and caveolin-1 in tumor necrosis factor alpha-induced endothelial cell activation. 2008 Oct 1
73 18805401 Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation. 2008 Nov 15 1
74 19052522 Berberine suppresses TNF-alpha-induced MMP-9 and cell invasion through inhibition of AP-1 activity in MDA-MB-231 human breast cancer cells. 2008 Dec 3 1
75 17126905 Differential regulation of TNFalpha and GM-CSF induced activation of P38 MAPK in neutrophils and eosinophils. 2007 Mar 1
76 17178391 Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases. 2007 Feb 1
77 17339845 Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells. 2007 Apr 1
78 17348859 Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. 2007 Jun 1 1
79 17464346 The inhibitory effect of simvastatin on the ADMA-induced inflammatory reaction is mediated by MAPK pathways in endothelial cells. 2007 Feb 1
80 17697615 [High mobility group box 1 is increased in children with acute lymphocytic leukemia and stimulates the release of tumor necrosis factor-alpha in leukemic cell]. 2007 May 1
81 18028805 [The effects of p38 mitogen activated protein kinase inhibitor SB203580 on colonic mucosa tumor necrosis factor alpha expression in ulcerative colitis]. 2007 Sep 2
82 16517732 Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production. 2006 Mar 15 1
83 16720051 Protein tyrosine kinase and p38 MAP kinase pathways are involved in stimulation of matrix metalloproteinase-9 by TNF-alpha in human monocytes. 2006 Jul 15 1
84 16761312 Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages. 2006 Jul 1
85 16937467 DA-9601, a standardized extract of Artemisia asiatica, blocks TNF-alpha-induced IL-8 and CCL20 production by inhibiting p38 kinase and NF-kappaB pathways in human gastric epithelial cells. 2006 Aug 14 1
86 17015957 Infliximab neutralizes the suppressive effect of TNF-alpha on expression of extracellular-superoxide dismutase in vitro. 2006 Oct 2
87 17052676 Induction of adhesion molecules upon the interaction between eosinophils and bronchial epithelial cells: involvement of p38 MAPK and NF-kappaB. 2006 Dec 5 1
88 17058806 Low-dose lipopolysaccharide modifies the production of IL-12 by dendritic cells in response to various cytokines. 2006 Mar 1
89 15590691 Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. 2005 Feb 25 1
90 15633106 Inhibition of p38 mitogen-activated protein kinase ameliorates cytokine up-regulated shigatoxin-1 toxicity in human brain microvascular endothelial cells. 2005 Feb 1 3
91 15707402 Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function. 2005 Mar 1
92 15753227 p38 mitogen-activated protein kinase downregulates endothelial progenitor cells. 2005 Mar 8 1
93 15897117 [Advanced oxidation protein products-induced tumor necrosis factor alpha secretion in monocytes via reactive oxygen species generation]. 2005 May 1
94 12954601 Actin reorganization and morphological changes in human neutrophils stimulated by TNF, GM-CSF, and G-CSF: the role of MAP kinases. 2004 Jan 1
95 14602083 Protein kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia. 2004 Mar 1
96 14715932 Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. 2004 Jan 7 1
97 14751545 Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in human tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB. 2004 May 1
98 14757367 Serum amyloid A-induced mRNA expression and release of tumor necrosis factor-alpha (TNF-alpha) in human neutrophils. 2004 Jan 30 1
99 14980382 Dissection of tumor-necrosis factor-alpha inhibition of long-term potentiation (LTP) reveals a p38 mitogen-activated protein kinase-dependent mechanism which maps to early-but not late-phase LTP. 2004 3
100 14998552 Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression. 2004 May 1