Title : Inhibition of p38 pathway suppresses human islet production of pro-inflammatory cytokines and improves islet graft function.

Pub. Date : 2005 Mar

PMID : 15707402






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1 Our present study has demonstrated that inhibition of the p38 pathway by a chemical p38 inhibitor, SB203580, suppresses IL-1beta and TNF-alpha production in human islets exposed to lipopolysaccharide (LPS) and/or inflammatory cytokines. SB 203580 tumor necrosis factor Homo sapiens