| 1 |
30015051 | Molecular mechanism of D816X mutation-induced c-Kit activation and -mediated inhibitor resistance in gastrointestinal stromal tumor. | 2018 Sep |
1 |
| 2 |
21135090 | Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells. | 2011 Feb 25 |
1 |
| 3 |
21640708 | Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816. | 2011 Jul 1 |
1 |
| 4 |
19540337 | Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3. | 2009 Dec |
1 |
| 5 |
19915299 | Successful treatment of KIT D816V-positive, imatinib-resistant systemic mastocytosis with interferon-alpha. | 2009 |
1 |
| 6 |
17173066 | Semaxinib (SU5416) as a therapeutic agent targeting oncogenic Kit mutants resistant to imatinib mesylate. | 2007 May 31 |
2 |
| 7 |
15542581 | PKCdelta plays opposite roles in growth mediated by wild-type Kit and an oncogenic Kit mutant. | 2005 Mar 1 |
1 |
| 8 |
16242000 | CD117+ small cell lung cancer lacks the asp 816-->val point mutation in exon 17. | 2005 Nov |
1 |
| 9 |
16352739 | Mastocytosis in mice expressing human Kit receptor with the activating Asp816Val mutation. | 2005 Dec 19 |
1 |
| 10 |
12111653 | Amplification of a novel c-Kit activating mutation Asn(822)-Lys in the Kasumi-1 cell line: a t(8;21)-Kit mutant model for acute myeloid leukemia. | 2002 |
1 |
| 11 |
12363464 | Detection of c-kit point mutation Asp-816 --> Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia. | 2002 Nov |
2 |
| 12 |
11369651 | Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-Kit-mediated cytokine-independent survival and proliferation in human leukemia cells. | 2001 Jun 1 |
6 |
| 13 |
11378569 | Activating mutations of c-kit at codon 816 confer drug resistance in human leukemia cells. | 2001 May |
2 |
| 14 |
11494148 | STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity. | 2001 Jul 27 |
6 |
| 15 |
9990072 | Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. | 1999 Feb 16 |
1 |
| 16 |
8547652 | Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain. | 1996 Jan 1 |
1 |
| 17 |
7536501 | Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3. | 1995 Apr |
1 |
| 18 |
7512180 | Activating mutations of the c-kit proto-oncogene in a human mast cell leukemia cell line. | 1994 Apr |
1 |
| 19 |
7691885 | Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. | 1993 Oct |
1 |